Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.50 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4391411 | 1.00 | CRBN (0.50) | CRBNDDB1IKZF3 | |
| SCHEMBL4388079 | 0.87 | CRBN (0.53) | CRBNDDB1IKZF3 | |
| SCHEMBL4388075 | 0.87 | CRBN (0.53) | CRBNDDB1IKZF3 | |
| SCHEMBL4400886 | 0.85 | CRBN (0.56) | CRBNDDB1 | |
| SCHEMBL4400882 | 0.85 | CRBN (0.56) | CRBNDDB1 | |
| SCHEMBL7266665 | 0.84 | CRBN (0.49) | CRBNDDB1IKZF3 | |
| SCHEMBL7266677 | 0.84 | CRBN (0.49) | CRBNDDB1IKZF3 | |
| SCHEMBL4400598 | 0.83 | CRBN (0.56) | CRBNDDB1IKZF3 | |
| SCHEMBL4400590 | 0.83 | CRBN (0.56) | CRBNDDB1IKZF3 | |
| SCHEMBL7266737 | 0.81 | CRBN (0.45) | CRBNDDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252144-B1 | SUBSTITUTED GLUTARIMIDES AND USE THEREOF IL-12 PRODUCTION INHIBITORS | GRUENENTHAL GMBH (DE) | 2009-12-09 | — | — | EP | claimed |