SCHEMBL4391479

SCHEMBL4391479

Nc1csc(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL19329323 0.97
SCHEMBL1764309 0.67
SCHEMBL1196519 0.65
SCHEMBL3166047 0.65
SCHEMBL28571882 0.65
Ammonia Solution, Strong SCHEMBL23116686 0.65
SCHEMBL23003708 0.65
SCHEMBL18830967 0.65
Hydrochloric Acid SCHEMBL355027 0.64
Hydrochloric Acid SCHEMBL10489602 0.63 IKBKB (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118852197-A Apigenin derivative and preparation method and application thereof 常州康安生物科技有限公司 2024-10-29 CN claimed
US-7297168-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2007-11-20 US claimed
US-20050198745-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-09-15 US claimed
US-20040102450-A1 Substituted oxoazaheterocyclyl compounds AVENTIS PHARMACEUTICALS INC. (US) 2004-05-27 US claimed
EP-1051176-A4 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARM PROD INC (US) 2002-06-12 EP claimed
JP-2002501024-A 2002-01-15 JP claimed
EP-1051176-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS Aventis Pharmaceuticals Products Inc. (US) 2000-11-15 EP claimed
WO-1999037304-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-07-29 WO claimed
EP-0311033-A2 3-Phthalimidothiophenes or their addition products with morpholine, process for their preparation, their use in the preparation of 3-amino-thiophenes and the 3-amino-5-chlorthiopene HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-12 EP claimed
CN-118978521-A Preparation method and application of fused ring compound 江苏普莱医药生物技术有限公司 2024-11-19 CN disclosed
CN-118852197-A Apigenin derivative and preparation method and application thereof 常州康安生物科技有限公司 2024-10-29 CN disclosed
CN-117624140-A CXCR4 antagonists, methods of making and uses thereof 杭州师范大学 2024-03-01 CN disclosed
CN-109071560-B Thienopyridine carboxamides as ubiquitin-specific protease inhibitors 瓦洛健康公司 2022-01-14 CN disclosed
WO-2021122434-A1 COMBINATION OF AN AHR-INHIBITOR AND AN PD1-INHIBITOR ANTIBODY AND ITS USE IN THE TREATMENT OF CANCER BAYER AKTIENGESELLSCHAFT (DE) 2021-06-24 WO disclosed
WO-1999037304-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-07-29 WO disclosed
EP-0311033-A2 3-Phthalimidothiophenes or their addition products with morpholine, process for their preparation, their use in the preparation of 3-amino-thiophenes and the 3-amino-5-chlorthiopene HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-12 EP disclosed
EP-0311033-A2 3-Phthalimidothiophenes or their addition products with morpholine, process for their preparation, their use in the preparation of 3-amino-thiophenes and the 3-amino-5-chlorthiopene HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-12 EP disclosed
EP-0311033-A2 3-Phthalimidothiophenes or their addition products with morpholine, process for their preparation, their use in the preparation of 3-amino-thiophenes and the 3-amino-5-chlorthiopene HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-12 EP disclosed
US-4263205-A FOR COLORING POLYMERS, LACQUERS CIBA-GEIGY CORPORATION (US) 1981-04-21 US disclosed
EP-0006154-A1 Monoazo pigments and their use in colouring high molecular-weight organic material CIBA-GEIGY AG (CH) 1980-01-09 EP disclosed