Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.67 |
| ▸ | GRM6 | O15303 | 1/20 | 0.67 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.67 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.67 |
| ▸ | GSR | P00390 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.67 |
| ▸ | GRM5 | P41594 | 1/20 | 0.67 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.67 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.67 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.67 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.67 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.67 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.67 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.67 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.67 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.67 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.67 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.67 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Myristic Acid SCHEMBL28211043 | 1.00 | GRM8 (0.67) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Dodecanoate SCHEMBL28392111 | 1.00 | GRM8 (0.67) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Octanoic Acid SCHEMBL28246078 | 1.00 | GRM8 (0.67) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Decanoic Acid SCHEMBL1045578 | 1.00 | GRM8 (0.67) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Palmitic Acid SCHEMBL4391708 | 1.00 | GRM8 (0.67) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Stearic Acid SCHEMBL4391220 | 1.00 | GRM8 (0.67) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Dodecanoate SCHEMBL28371028 | 1.00 | GRM8 (0.67) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Decanoic Acid SCHEMBL6751319 | 1.00 | GRM8 (0.67) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Stearic Acid SCHEMBL4391222 | 1.00 | GRM8 (0.67) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Decanoic Acid SCHEMBL13278749 | 0.98 | GRM8 (0.64) | GRM8GRM6GRIN2DGRIN3BGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240168035-A1 | METHODS FOR QUANTIFYING DRUG CONCENTRATION IN A PRODRUG COMPOSITION | GENZYME CORPORATION | 2024-05-23 | — | — | US | disclosed |
| US-11796546-B2 | Methods for quantifying drug concentration in a prodrug composition | GENZYME CORPORATION (US) | 2023-10-24 | — | — | US | disclosed |
| EP-3966343-A1 | METHODS FOR QUANTIFYING DRUG CONCENTRATION IN A PRODRUG COMPOSITION | Genzyme Corporation (US) | 2022-03-16 | — | — | EP | disclosed |
| CN-113984911-A | Chromatographic method for simultaneously analyzing liraglutide and Boc-liraglutide main chain thereof | 宁波鲲鹏生物科技有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-113795590-A | Method for quantifying drug concentration in prodrug composition | 建新公司 | 2021-12-14 | — | — | CN | disclosed |
| CN-113135990-A | Liraglutide derivatives and preparation method thereof | 宁波鲲鹏生物科技有限公司 | 2021-07-20 | — | — | CN | disclosed |
| US-20200386768-A1 | METHODS FOR QUANTIFYING DRUG CONCENTRATION IN A PRODRUG COMPOSITION | GENZYME CORPORATION | 2020-12-10 | — | — | US | disclosed |
| WO-2020227364-A1 | METHODS FOR QUANTIFYING DRUG CONCENTRATION IN A PRODRUG COMPOSITION | GENZYME CORPORATION (US) | 2020-11-12 | — | — | WO | disclosed |
| US-10175233-B2 | Biomarkers for cardiovascular diseases and methods using the same | METABOLON, INC. (US) | 2019-01-08 | — | — | US | disclosed |
| CN-107108715-A | The co-agonists of hyperglycemic factor and the acceptors of GLP 1 | 默沙东公司 | 2017-08-29 | — | — | CN | disclosed |
| US-20160178620-A1 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and other Metabolic-Syndrome Related Disorders and Methods Using the Same | METABOLON, INC. | 2016-06-23 | — | — | US | disclosed |
| US-9250225-B2 | Biomarkers for insulin resistance and methods using the same | METABOLON, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-20150005195-A1 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and Other Metabolic-Syndrome Related Disorders and Methods Using the Same | METABOLON, INC. | 2015-01-01 | — | — | US | disclosed |
| US-8809008-B2 | Biomarkers for impaired glucose tolerance and methods using the same | METABOLON, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-20130338031-A1 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and Other Metabolic-Syndrome Related Disorders and Methods Using the Same | METABOLON, INC. | 2013-12-19 | — | — | US | disclosed |
| EP-2164977-B1 | BIOMARKERS FOR PRE-DIABETES AND METHODS USING THE SAME | METABOLON INC (US) | 2013-10-30 | — | — | EP | disclosed |
| US-8546098-B2 | Biomarkers for monitoring insulin resistance and methods using the same | METABOLON, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120208215-A1 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and Other Metabolic-Syndrome Related Disorders and Methods Using the Same | METABOLON, INC. (US) | 2012-08-16 | — | — | US | disclosed |
| US-8187830-B2 | Method for determining insulin sensitivity with biomarkers | METABOLON, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20090155826-A1 | Biomarkers for pre-diabetes, cardiovascular diseases, and other metabolic-syndrome related disorders and methods using the same | METABOLON, INC. (US) | 2009-06-18 | — | — | US | disclosed |