SCHEMBL4392248

SCHEMBL4392248

CCCCOCCOC[O]

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
CYP3A4 P08684 2/20 0.56
MEN1 O00255 1/20 0.46
THRB P10828 1/20 0.46
HTT P42858 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPT P10636 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.43
HPGD P15428 2/20 0.43
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39
ALDH1A1 P00352 3/20 0.39
CES2 O00748 2/20 0.38
RARB P10826 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
ATM Q13315 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9488044 1.00 TSHR (0.56) TSHRCYP3A4MEN1THRBHTT
SCHEMBL4390963 0.94 TSHR (0.52) TSHRCYP3A4MEN1THRBHTT
SCHEMBL4396242 0.94 TSHR (0.52) TSHRCYP3A4MEN1THRBHTT
SCHEMBL380036 0.94
SCHEMBL8810737 0.92 MEN1 (0.56) TSHRCYP3A4MEN1THRBHTT
SCHEMBL8811432 0.92 TSHR (0.50) TSHRCYP3A4MEN1THRBHTT
SCHEMBL8811016 0.92 TSHR (0.50) TSHRCYP3A4MEN1THRBHTT
SCHEMBL8814294 0.86 MEN1 (0.56) TSHRCYP3A4MEN1THRBHTT
SCHEMBL8813129 0.86 MEN1 (0.56) TSHRCYP3A4MEN1THRBHTT
SCHEMBL379913 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0260689-B1 NAPHTHOLACTAM QUADRATIC-ACID DYES AND OPTICAL REGISTRATION MATERIALS CONTAINING THEM BASF Aktiengesellschaft (DE) 1993-02-03 EP claimed
US-4830951-A HIGH SENSITIVITY TO SEMICONDUCTOR LASERS BASF AKTIENGESELLSCHAFT (DE) 1989-05-16 US claimed
EP-0260689-A2 Naphtholactam quadratic-acid dyes and optical registration materials containing them BASF Aktiengesellschaft (DE) 1988-03-23 EP claimed
US-20090306376-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME MITSUI CHEMICALS, INC. (JP) 2009-12-10 US disclosed
US-7405030-B2 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2008-07-29 US disclosed
EP-1930339-A2 Imide compound MITSUI CHEMICALS, INC. (JP) 2008-06-11 EP disclosed
US-20070259151-A1 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2007-11-08 US disclosed
US-7259260-B2 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2007-08-21 US disclosed
US-20070054084-A1 Optical recording medium and compound used for the same MITSUI CHEMICALS, INC. (JP) 2007-03-08 US disclosed
US-7094516-B2 Benzobisazole compound and optical recording medium containing the compound MITSUI CHEMICALS, INC. (JP) 2006-08-22 US disclosed
EP-1672626-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED IN THE OPTICAL RECORDING MEDIUM Mitsui Chemicals, Inc. (JP) 2006-06-21 EP disclosed
EP-0260689-B1 NAPHTHOLACTAM QUADRATIC-ACID DYES AND OPTICAL REGISTRATION MATERIALS CONTAINING THEM BASF Aktiengesellschaft (DE) 1993-02-03 EP disclosed
US-4830951-A HIGH SENSITIVITY TO SEMICONDUCTOR LASERS BASF AKTIENGESELLSCHAFT (DE) 1989-05-16 US disclosed
EP-0260689-A2 Naphtholactam quadratic-acid dyes and optical registration materials containing them BASF Aktiengesellschaft (DE) 1988-03-23 EP disclosed
US-4604460-A ANTIBIOTICS, BACTERICIDES SHIONOGI & CO., LTD. (JP) 1986-08-05 US disclosed
US-4533730-A BACTERICIDES SHIONOGI & CO., LTD. (JP) 1985-08-06 US disclosed
US-4504659-A 1-Oxadethiacepham compounds SHIONOGI & CO., LTD. (JP) 1985-03-12 US disclosed
US-4478997-A 1-Oxadethiacepham compounds SHIONOGI & CO., LTD. (JP) 1984-10-23 US disclosed
US-4443598-A ANTIBIOTICS AND INTERMEDIATES SHIONOGI & CO., LTD. (JP) 1984-04-17 US disclosed
US-4366316-A FROM OXAZOLINOAZETIDINONE AND ACID SHIONOGI & CO., LTD. (JP) 1982-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306376-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME CACNA1B, KCNN4, KCNN2 TSHR 3610/4885CYP3A4 2777/4885MEN1 979/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.