Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDUA | P35475 | 1/20 | 0.47 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21067530 | 1.00 | IDUA (0.47) | IDUAFUCA1GBA1GAA | |
| SCHEMBL21067531 | 1.00 | IDUA (0.47) | IDUAFUCA1GBA1GAA | |
| SCHEMBL16629463 | 0.78 | IDUA (0.31) | IDUA | |
| SCHEMBL263944 | 0.78 | IDUA (0.31) | IDUA | |
| SCHEMBL15828336 | 0.78 | IDUA (0.31) | IDUA | |
| SCHEMBL3982668 | 0.77 | — | — | |
| SCHEMBL3982678 | 0.77 | — | — | |
| SCHEMBL3975872 | 0.77 | — | — | |
| SCHEMBL3975869 | 0.77 | — | — | |
| SCHEMBL18016480 | 0.74 | FUCA1 (0.32) | FUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090041740-A1 | CANCER TREATMENT BY METABOLIC MODULATIONS | ENGENE, INC. (CA) | 2009-02-12 | — | — | US | disclosed |
| US-20050202559-A1 | Cancer treatment by metabolic modulations | HERCULES CAPITAL, INC. | 2005-09-15 | — | — | US | disclosed |
| EP-1556088-A2 | COMPOSITIONS FOR CANCER TREATMENT | Engene, Inc. (CA) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039412-A2 | COMPOSITIONS FOR CANCER TREATMENT | ENGENE, INC. (CA) | 2004-05-13 | — | — | WO | disclosed |