Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 4/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4393488 | 0.91 | CXCR4 (0.39) | CXCR4 | |
| SCHEMBL4079115 | 0.88 | CXCR4 (0.39) | CXCR4MEN1MAPTMAPK1KMT2A | |
| SCHEMBL4529738 | 0.84 | CXCR4 (0.37) | CXCR4MEN1MAPTMAPK1KMT2A | |
| SCHEMBL4068901 | 0.82 | CXCR4 (0.38) | CXCR4MEN1MAPTMAPK1KMT2A | |
| SCHEMBL4066966 | 0.81 | CXCR4 (0.54) | CXCR4MEN1MAPTMAPK1KMT2A | |
| SCHEMBL4072227 | 0.80 | CXCR4 (0.42) | CXCR4MEN1MAPTMAPK1KMT2A | |
| SCHEMBL4073790 | 0.80 | CXCR4 (0.53) | CXCR4TBXAS1 | |
| SCHEMBL4069146 | 0.80 | CXCR4 (0.42) | CXCR4TBXAS1 | |
| SCHEMBL4067781 | 0.80 | CXCR4 (0.53) | CXCR4TBXAS1 | |
| SCHEMBL4075534 | 0.80 | CXCR4 (0.43) | CXCR4MEN1MAPTMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2055705-A1 | COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF | Ono Pharmaceutical CO., LTD. (JP) | 2009-05-06 | — | — | EP | disclosed |