Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.79 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29035619 | 1.00 | TSHR (0.79) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL29035560 | 1.00 | TSHR (0.79) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL336350 | 0.98 | TSHR (0.75) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28624268 | 0.94 | TSHR (0.68) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL13945622 | 0.89 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL33725 | 0.89 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9101988 | 0.89 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8493780 | 0.89 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL322713 | 0.89 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL13283404 | 0.89 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110508222-A | Monodisperse core-shell particles and preparation method thereof with mesoporous silicon oxide shell | UNIV FUDAN | 2019-11-29 | — | — | CN | claimed |
| CN-110392708-A | Adhesive composition based on graft resin | 洛德公司 | 2019-10-29 | — | — | CN | claimed |
| CN-109843229-A | By the pinpoint accuracy drug delivery of dual domain device for eyes | 领视药公司 | 2019-06-04 | — | — | CN | claimed |
| CN-109820279-A | A kind of preparation method of the antifreeze foot warming shoe of waterproof | 浙江太极鞋业有限公司 | 2019-05-31 | — | — | CN | claimed |
| CN-109793312-A | A kind of preparation method of health care playshoes | 浙江太极鞋业有限公司 | 2019-05-24 | — | — | CN | claimed |
| CN-109790243-A | Three block prepolymer and its purposes in silicone hydrogels | 庄臣及庄臣视力保护公司 | 2019-05-21 | — | — | CN | claimed |
| CN-109749029-A | A kind of high molecular polymer and preparation method and application | 兰州理工大学 | 2019-05-14 | — | — | CN | claimed |
| CN-109730402-A | A kind of playshoes and preparation method with double-purpose functional | 浙江太极鞋业有限公司 | 2019-05-10 | — | — | CN | claimed |
| CN-107304051-B | A kind of inorganic nano Porous materials and preparation method thereof | 中国科学院化学研究所 | 2019-03-26 | — | — | CN | claimed |
| CN-109476824-A | Bi-component plaster material and application thereof | 喜利得股份公司 | 2019-03-15 | — | — | CN | claimed |
| CN-105164555-A | Primary amine-containing silicone hydrogel contact lenses and related compositions and methods | COOPERVISION INT HOLDING CO LP | 2015-12-16 | — | — | CN | claimed |
| CN-105074506-A | Silicone-containing contact lens having clay treatment applied thereto | JOHNSON & JOHNSON VISION CARE | 2015-11-18 | — | — | CN | claimed |
| CN-105008115-A | Silicone-containing contact lens having reduced amount of silicon on the surface | JOHNSON & JOHNSON VISION CARE | 2015-10-28 | — | — | CN | claimed |
| CN-104640894-A | Two-component polyurethane composition | SIKA TECHNOLOGY AG | 2015-05-20 | — | — | CN | claimed |
| CN-102219439-B | Chemical two component mortar composition with improved adhesion to the surface of semi-purified and/or wet bore holes in mineral base and use of same | HILTI AG | 2015-03-25 | — | — | CN | claimed |
| CN-104379330-A | Lens comprising low molecular weight polyamide and high molecular weight polyamide | JOHNSON & JOHNSON VISION CARE | 2015-02-25 | — | — | CN | claimed |
| CN-102171589-B | Ionic silicone hydrogels having improved hydrolytic stability | JOHNSON & JOHNSON VISION CARE | 2015-01-14 | — | — | CN | claimed |
| EP-0449413-B1 | Polymers | ICI PLC (GB) | 1995-12-20 | — | — | EP | claimed |
| US-5274064-A | An addition polymer having a \"hub\" of a tri-to octathiol; crosslinking | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-28 | — | — | US | claimed |
| EP-0449413-A1 | Polymers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-02 | — | — | EP | claimed |