⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodoacetamide SCHEMBL31146774 | 0.76 | — | — | |
| Iodoacetamide SCHEMBL20371 | 0.76 | — | — | |
| Iodoacetamide SCHEMBL1332134 | 0.76 | — | — | |
| Iodoacetamide SCHEMBL29006525 | 0.73 | — | — | |
| Iodoacetamide SCHEMBL5993617 | 0.73 | — | — | |
| Iodoacetamide SCHEMBL25246804 | 0.73 | — | — | |
| Iodoacetamide SCHEMBL2361208 | 0.73 | — | — | |
| Iodoacetamide SCHEMBL597976 | 0.73 | — | — | |
| Iodoacetamide SCHEMBL8333021 | 0.73 | — | — | |
| SCHEMBL96959 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1998 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936487-B | Compounds for the treatment of kinase dependent disorders | 埃克塞里艾克西斯公司 | 2024-07-09 | — | — | CN | claimed |
| US-20240150371-A1 | Compounds for the Treatment of Kinase-Dependent Disorders | EXELIXIS, INC. | 2024-05-09 | — | — | US | claimed |
| CN-113710664-B | JAK1 selective kinase inhibitors | 迪哲(江苏)医药股份有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-116354964-A | 7 (8H) -pteridinone derivatives as BTK inhibitors and uses thereof | 华东理工大学 | 2023-06-30 | — | — | CN | claimed |
| US-20230148194-A1 | SUBSTITUTED AMINOQUINOLONES AS DGKALPHA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AKTIENGESELLSCHAFT (DE) | 2023-05-11 | — | — | US | claimed |
| US-20230135068-A1 | PYRAZINE COMPOUNDS AND USES THEREOF | DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) | 2023-05-04 | — | — | US | claimed |
| US-11571420-B2 | Pyrazine compounds and uses thereof | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-02-07 | — | — | US | claimed |
| CN-115003665-A | Substituted aminoquinolones as immunoactive DGK alpha inhibitors | 拜耳公司 | 2022-09-02 | — | — | CN | claimed |
| CN-112279837-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-08-09 | — | — | CN | claimed |
| US-20220220096-A1 | JAK1 SELECTIVE KINASE INHIBITOR | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2022-07-14 | — | — | US | claimed |
| US-4387099-A | Alkanolamine derivatives | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1983-06-07 | — | — | US | claimed |
| EP-0073145-A1 | A phenol cyan coupler for silver halide color photographic material | KONICA CORPORATION (JP) | 1983-03-02 | — | — | EP | claimed |
| EP-0073146-A1 | Method and material for the formation of silver halide color photographic image | KONICA CORPORATION (JP) | 1983-03-02 | — | — | EP | claimed |
| US-4327113-A | DRUGS FOR TREATMENT OF HEART DISEASES, ADRENERGIC BLOCKING AGENTS, ETC | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-04-27 | — | — | US | claimed |
| US-4299914-A | Method for forming a cyan dye image | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1981-11-10 | — | — | US | claimed |
| EP-0002774-B1 | PROCESS FOR ACYLATING 7AMINOCEPHEM DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-23 | — | — | EP | claimed |
| US-4260632-A | ADRENERGIC BLOCKING AGENTS, CARDIOVASCULAR DISORDERS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-04-07 | — | — | US | claimed |
| US-4221807-A | ADRENERGIC BLOCKING AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-09-09 | — | — | US | claimed |
| EP-0007019-A1 | 5-Phenyl-pyrazole derivatives and their salts, processes for their preparation and medicines containing them | Kali-Chemie Pharma GmbH (DE) | 1980-01-23 | — | — | EP | claimed |
| US-4141987-A | HYPOTENSIVE, ADRENERGIC BLOCKING AGENT | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-02-27 | — | — | US | claimed |