Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 20/20 | 0.82 |
| ▸ | CPT2 | P23786 | 13/20 | 0.82 |
| ▸ | CPT1B | Q92523 | 7/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3550593 | 1.00 | CPT1A (0.82) | CPT1ACPT2CPT1B | |
| SCHEMBL3550587 | 1.00 | CPT1A (0.82) | CPT1ACPT2CPT1B | |
| SCHEMBL3555428 | 0.94 | CPT1A (0.84) | CPT1ACPT2CPT1B | |
| SCHEMBL3555422 | 0.94 | CPT1A (0.84) | CPT1ACPT2CPT1B | |
| SCHEMBL3556955 | 0.91 | CPT1A (0.77) | CPT1ACPT2CPT1B | |
| SCHEMBL3556428 | 0.91 | CPT1A (0.77) | CPT1ACPT2CPT1B | |
| SCHEMBL3556433 | 0.91 | CPT1A (0.77) | CPT1ACPT2CPT1B | |
| SCHEMBL3555384 | 0.90 | CPT1A (1.00) | CPT1ACPT2CPT1B | |
| SCHEMBL3555396 | 0.90 | CPT1A (1.00) | CPT1ACPT2CPT1B | |
| SCHEMBL3555651 | 0.90 | CPT1A (0.78) | CPT1ACPT2CPT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959951-B1 | HETEROARYL SUBSTITUTED PIPERIDINE DERIVATIVES AS L-CPT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-12-23 | — | — | EP | disclosed |