Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.56 |
| ▸ | PTPN12 | Q05209 | 2/20 | 0.56 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.56 |
| ▸ | EP300 | Q09472 | 1/20 | 0.56 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.56 |
| ▸ | APAF1 | O14727 | 1/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4394189 | 0.93 | MEN1 (0.62) | STAT3MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL4394192 | 0.93 | MEN1 (0.62) | STAT3MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL13592708 | 0.93 | MEN1 (0.62) | STAT3MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL4396750 | 0.87 | EP300 (0.73) | STAT3MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL4396439 | 0.87 | EP300 (0.73) | STAT3MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL14045885 | 0.87 | MEN1 (0.63) | STAT3MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL14025843 | 0.87 | EP300 (0.73) | STAT3MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL4882130 | 0.85 | EP300 (0.75) | STAT3MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL4882126 | 0.85 | EP300 (0.75) | STAT3MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL4887861 | 0.85 | STAT3 (0.68) | STAT3MEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1830848-B1 | USE OF THIAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF SOLID TUMORS | CELL THERAPEUTICS EUROPE SRL (IT) | 2009-12-16 | — | — | EP | claimed |