SCHEMBL4394836

SCHEMBL4394836

NCC(=O)OC(=O)[C@H](N)CO

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL117468 1.00 SLC1A1 (0.31) SLC1A1
SCHEMBL16678086 0.86 SLC1A5 (0.36) SLC1A1
SCHEMBL2158686 0.83 SLC1A1 (0.37) SLC1A1
Serine SCHEMBL418634 0.82 PTGS1 (0.48) SLC1A1
Serine SCHEMBL3961258 0.82 SLC1A5 (0.36) SLC1A1
SCHEMBL5272389 0.80 SLC1A5 (0.33) SLC1A1
Serine SCHEMBL3052910 0.80 SLC1A5 (0.35) SLC1A1
Serine SCHEMBL1064689 0.80 SLC1A1 (0.43) SLC1A1
SCHEMBL361160 0.80 PTGS1 (0.44)
SCHEMBL307010 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11213522-B2 Autoimmune-induced glutamatergic receptor dysfunction methods and treatments SARAH HERZOG MEMORIAL HOSPITAL EZRAT NASHIM ASSOCIATION (IL) 2022-01-04 US disclosed
US-20200113894-A1 Autoimmune-Induced Glutamatergic Receptor Dysfunction Methods and Treatments SARAH HERZOG MEMORIAL HOSPITAL EZRAT NASHIM ASSOCIATION (IL) 2020-04-16 US disclosed
EP-1444979-B1 Pharmaceutical compositions comprising an NMDA receptor agonist for the treatment of movement disorders SARAH HERZOG MEMORIAL HOSPITAL (IL) 2009-12-16 EP disclosed