Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 11/20 | 0.61 |
| ▸ | PIK3CB | P42338 | 9/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.61 |
| ▸ | PIM1 | P11309 | 7/20 | 0.61 |
| ▸ | GSK3B | P49841 | 7/20 | 0.61 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 4/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458971 | 1.00 | PIK3CD (0.61) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 | |
| SCHEMBL13570073 | 1.00 | PIK3CD (0.61) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 | |
| SCHEMBL1781765 | 0.91 | PIK3CD (0.53) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 | |
| SCHEMBL1780764 | 0.88 | PIK3CD (0.64) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 | |
| SCHEMBL2215093 | 0.88 | PIK3CD (0.58) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 | |
| SCHEMBL1251729 | 0.87 | PIK3CD (0.63) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 | |
| SCHEMBL1779554 | 0.87 | PIK3CD (0.65) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 | |
| SCHEMBL1779958 | 0.87 | PIK3CD (0.57) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 | |
| SCHEMBL1252541 | 0.86 | PIK3CA (0.62) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 | |
| SCHEMBL463446 | 0.86 | PIK3CD (0.62) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147190-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-12-10 | — | — | WO | claimed |