⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15360079 | 0.76 | SMPD3 (0.44) | — | |
| SCHEMBL15034720 | 0.76 | MAPT (0.54) | — | |
| SCHEMBL27952255 | 0.74 | PIK3CB (0.41) | — | |
| SCHEMBL31227892 | 0.74 | — | — | |
| SCHEMBL20611026 | 0.74 | — | — | |
| SCHEMBL25428969 | 0.74 | — | — | |
| SCHEMBL23128404 | 0.74 | — | — | |
| SCHEMBL11250319 | 0.74 | — | — | |
| SCHEMBL12884843 | 0.74 | KDM4E (0.34) | — | |
| SCHEMBL24400469 | 0.74 | KDM4E (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873319-B2 | Cyclic di-nucleotide induction of type I interferon | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-01-16 | — | — | US | disclosed |
| US-20230416934-A1 | ACID-FREE PYROLYTIC SYNTHESIS OF M-N-C CATALYST | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-12-28 | — | — | US | disclosed |
| US-20230227474-A1 | COMPOSITIONS AND METHODS FOR CORRECTION OF ABERRANT SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-07-20 | — | — | US | disclosed |
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
| US-20230054781-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-02-23 | — | — | US | disclosed |
| US-20230009712-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-01-12 | — | — | US | disclosed |
| EP-4116310-A1 | METHOD FOR MANUFACTURING PHOSPHONATE ESTERS AND METHOD FOR MANUFACTURING PHOSPHATE ESTERS | FUJIFILM Wako Pure Chemical Corporation (JP) | 2023-01-11 | — | — | EP | disclosed |
| US-20220048890-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2022-02-17 | — | — | US | disclosed |
| EP-3707151-B1 | STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICALS CO (JP) | 2022-01-05 | — | — | EP | disclosed |
| EP-3912984-A1 | 4'-FLUORO-NUCLEOSIDES, 4'-FLUORO-NUCLEOTIDES AND ANALOGS THEREOF FOR THE TREATMENT OF HCV | Janssen BioPharma, Inc. (US) | 2021-11-24 | — | — | EP | disclosed |
| US-20080227676-A1 | Amine reaction compounds comprising one or more active ingredient | PROCTER & GAMBLE COMPANY, THE | 2008-09-18 | — | — | US | disclosed |
| US-20070232507-A1 | Amine reaction compounds comprising one or more active ingredient | THE PROCTER & GAMBLE COMPANY ATTENTION: CHIEF PATENT COUNSEL (US) | 2007-10-04 | — | — | US | disclosed |
| US-20070099818-A1 | Amine reaction compounds comprising one or more active ingredient | THE PROCTER & GAMBLE COMPANY (US) | 2007-05-03 | — | — | US | disclosed |
| US-7186700-B2 | β-L-2′-deoxynucleosides for the treatment of resistant HBV strains and combination therapies | IDENIX PHARMACEUTICALS, INC. (US) | 2007-03-06 | — | — | US | disclosed |
| CN-1288157-C | Dioxinopyridine compounds for the treatment of impaired fundic relaxation, process for their preparation and their use | JANSSEN PHARMACEUTICA NV (BE) | 2006-12-06 | — | — | CN | disclosed |
| CN-1781921-A | Compounds for treating impaired fundic relaxation | JANSSEN PHARMACEUTICA NV (BE) | 2006-06-07 | — | — | CN | disclosed |
| CN-1437602-A | Compounds for treating impaired fundic relaxation | JANSSEN PHARMACEUTICA NV (BE) | 2003-08-20 | — | — | CN | disclosed |
| CN-1092420-A | Compound | GLAXO GROUP LTD (GB) | 1994-09-21 | — | — | CN | disclosed |
| CN-86108620-A | Pyridine derivate and manufacture method thereof contain the preparation of these compounds and as the application of agricultural chemicals | — | 1987-08-05 | — | — | CN | disclosed |
| US-4395406-A | 5-Halopyrimid-2-ones | NYEGAARD & CO. A/S (NO) | 1983-07-26 | — | — | US | disclosed |