SCHEMBL439669

SCHEMBL439669

Cc1ccc(C(C)(C)CN)cc1C(C)(C)CN

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.47
HTR1D P28221 1/20 0.34
KIF11 P52732 1/20 0.33
ESR1 P03372 2/20 0.32
CNR1 P21554 5/20 0.32
CNR2 P34972 5/20 0.32
NEK1 Q96PY6 1/20 0.32
PRKCQ Q04759 1/20 0.31
AR P10275 1/20 0.31
ESR2 Q92731 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8507806 0.85 TAAR1 (0.52) TAAR1HTR1DKIF11ESR1CNR1
SCHEMBL5983335 0.78 TAAR1 (0.45) TAAR1ESR1CNR1CNR2NEK1
SCHEMBL5983215 0.78 TAAR1 (0.45) TAAR1PRKCQ
SCHEMBL6562809 0.75 TAAR1 (0.75) TAAR1ESR1NEK1ARESR2
Hydrochloric Acid SCHEMBL6563360 0.73 TAAR1 (0.71) TAAR1ESR1NEK1ESR2
SCHEMBL30634176 0.72 TAAR1 (0.52) TAAR1KIF11
SCHEMBL10608288 0.72 TAAR1 (0.52) TAAR1KIF11
SCHEMBL24017229 0.72 ESR1 (0.38) HTR1DESR1ARESR2POLB
SCHEMBL9838530 0.72 HTR1D (0.32) TAAR1HTR1DKIF11
SCHEMBL10884558 0.72 MEN1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1564 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11905381-B2 Polyimide microparticles XEROX CORPORATION (US) 2024-02-20 US claimed
EP-4089136-A1 POLYIMIDE MICROPARTICLES Xerox Corporation (US) 2022-11-16 EP claimed
US-11021606-B2 Multilayer film for electronic circuitry applications E I DU PONT DE NEMOURS AND COMPANY (US) 2021-06-01 US claimed
US-20190284341-A1 3-OXO-2-ALKYLISOINDOLINE DIPHTHALONITRILE MONOMERS, METHODS OF MANUFACTURE, THERMOSETTING COMPOSITIONS COMPRISING THE SAME, AND USES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-09-19 US claimed
US-20190284339-A1 THERMOSET 3-OXO-ISOINDOLINE DIPHTHALONITRILE POLYMERS, METHOD OF MANUFACTURE, AND USES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-09-19 US claimed
US-20190284340-A1 3-OXO-2-ARYLISOINDOLINE DIPHTHALONITRILE MONOMERS, METHODS OF MANUFACTURE, THERMOSETTING COMPOSITIONS COMPRISING THE SAME, AND USES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-09-19 US claimed
EP-3539948-A1 3-OXO-2-ARYLISOINDOLINE DIPHTHALONITRILE MONOMERS, METHODS OF MANUFACTURE, THERMOSETTING COMPOSITIONS COMPRISING THE SAME, AND USES THEREOF SABIC Global Technologies B.V. (NL) 2019-09-18 EP claimed
EP-3539950-A1 3-OXO-2-ALKYLISOINDOLINE DIPHTHALONITRILE MONOMERS, METHODS OF MANUFACTURE, THERMOSETTING COMPOSITIONS COMPRISING THE SAME, AND USES THEREOF SABIC Global Technologies B.V. (NL) 2019-09-18 EP claimed
US-8545988-B2 Polyetherimide and polyetherimide sulfone blends having automotive lighting applications SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-10-01 US claimed
US-20130171459-A1 POLYAMIC ACID RESIN SOLUTION CONTAINING INTERPENETRATING POLYMER AND LAMINATE USING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-07-04 US claimed
WO-2003040213-A1 HIGH MOLECULAR WEIGHT POLY(IMIDE)S AND METHODS OF SYNTHESIS THEREOF GENERAL ELECTRIC COMPANY (US) 2003-05-15 WO claimed
EP-1287076-A2 HIGH PERFORMANCE THERMOPLASTIC COMPOSITIONS WITH IMPROVED MELT FLOW PROPERTIES GENERAL ELECTRIC COMPANY (US) 2003-03-05 EP claimed
US-6500904-B1 FROM THE COUPLING OF LOWER MOLECULAR WEIGHT FUNCTIONALIZED PRECURSOR POLYIMIDES GENERAL ELECTRIC COMPANY 2002-12-31 US claimed
US-6498224-B1 SOLUTION POLYMERIZATION OF A DIANHYDRIDE AND A DIAMINE WHICH ELIMINATES THE NITRATION STEP; HIGH HEAT ENGINEERING PLASTICS GENERAL ELECTRIC COMPANY 2002-12-24 US claimed
US-6350514-B1 POLYARYLENE ETHER AND POLYALKYLENEAROMATIC POLYMERS WITH AROMATIC AMINE FOR AUTOMOBILE INTERIORS WITH POLYURETHANES GENERAL ELECTRIC CO. 2002-02-26 US claimed
WO-2001096477-A2 HIGH PERFORMANCE THERMOPLASTIC COMPOSITIONS WITH IMPROVED MELT FLOW PROPERTIES GENERAL ELECTRIC COMPANY (US) 2001-12-20 WO claimed
US-5292854-A Synthesis of phthalonitrile resins containing ether and imide linkages with aromatic diamine curing agent THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1994-03-08 US claimed
US-5132396-A Phthalonitrile monomers containing imide and/or phenoxy linkages, and polymers thereof THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1992-07-21 US claimed
US-4008195-A POLYESTER NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) 1977-02-15 US claimed
US-3936404-A Aqueous baking varnishes from carboxylic polyester and carboxylic polyimide, and coated article NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) 1976-02-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190284341-A1 3-OXO-2-ALKYLISOINDOLINE DIPHTHALONITRILE MONOMERS, METHODS OF MANUFACTURE, THERMOSETTING COMPOSITIONS COMPRISING THE SAME, AND USES THEREOF CYP1B1, CYP2J2, CYP1A1 TAAR1 2578/4885HTR1D 319/4885KIF11 2418/4885
US-20190284340-A1 3-OXO-2-ARYLISOINDOLINE DIPHTHALONITRILE MONOMERS, METHODS OF MANUFACTURE, THERMOSETTING COMPOSITIONS COMPRISING THE SAME, AND USES THEREOF CYP1B1, CYP1A1, RECQL TAAR1 3124/4885HTR1D 192/4885KIF11 2731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.