Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 20/20 | 0.60 |
| ▸ | CPT2 | P23786 | 11/20 | 0.60 |
| ▸ | CPT1B | Q92523 | 5/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3553478 | 0.89 | CPT1A (0.64) | CPT1ACPT2CPT1B | |
| SCHEMBL4392366 | 0.84 | CPT1A (0.62) | CPT1ACPT2CPT1B | |
| SCHEMBL3552496 | 0.82 | CPT1A (0.86) | CPT1ACPT2CPT1B | |
| SCHEMBL3552493 | 0.82 | CPT1A (0.86) | CPT1ACPT2CPT1B | |
| SCHEMBL3555176 | 0.82 | CPT1A (0.74) | CPT1ACPT2CPT1B | |
| SCHEMBL3557165 | 0.81 | CPT1A (0.62) | CPT1ACPT2CPT1B | |
| SCHEMBL3552985 | 0.80 | CPT1A (0.73) | CPT1ACPT2CPT1B | |
| SCHEMBL3560848 | 0.80 | CPT1A (0.60) | CPT1ACPT2CPT1B | |
| SCHEMBL4399738 | 0.80 | CPT1A (0.72) | CPT1ACPT2CPT1B | |
| SCHEMBL3557923 | 0.79 | CPT1A (0.75) | CPT1ACPT2CPT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959951-B1 | HETEROARYL SUBSTITUTED PIPERIDINE DERIVATIVES AS L-CPT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-12-23 | — | — | EP | disclosed |