SCHEMBL4397323

SCHEMBL4397323

COc1ccc(C(=O)O)cc1NC(=O)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CASR P41180 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL925787 0.94 CASR (0.74) CASR
SCHEMBL926039 0.87 CASR (0.62) CASR
SCHEMBL926930 0.85 CASR (0.77) CASR
SCHEMBL926284 0.84 CASR (0.74) CASR
SCHEMBL926177 0.82 CASR (1.00) CASR
SCHEMBL926089 0.80 CASR (1.00) CASR
SCHEMBL926237 0.79 CASR (0.79) CASR
SCHEMBL927938 0.79 CASR (0.72) CASR
SCHEMBL926352 0.79 CASR (1.00) CASR
SCHEMBL926569 0.79 CASR (1.00) CASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1965805-B1 UREA DERIVATIVES USEFUL AS CALCIUM RECEPTOR MODULATORS GALAPAGOS SAS (FR) 2009-12-02 EP disclosed