Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | EDNRB | P24530 | 3/20 | 0.46 |
| ▸ | EDNRA | P25101 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CCR9 | P51686 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2806158 | 0.89 | KMT2A (0.45) | SERPINE1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL2810307 | 0.89 | SERPINE1 (0.41) | SERPINE1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL2808105 | 0.88 | SERPINE1 (0.43) | SERPINE1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL2807914 | 0.87 | SERPINE1 (0.54) | SERPINE1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL2810186 | 0.87 | SERPINE1 (0.54) | SERPINE1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL14270697 | 0.85 | KMT2A (0.53) | SERPINE1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL2810361 | 0.85 | SERPINE1 (0.51) | SERPINE1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL13168627 | 0.85 | KMT2A (0.40) | SERPINE1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL2807174 | 0.84 | SERPINE1 (0.61) | SERPINE1EDNRBEDNRACCR9FOLH1 | |
| SCHEMBL2813528 | 0.83 | SERPINE1 (0.50) | SERPINE1MEN1KMT2AALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081894-A1 | 1H-INDOLE-2-CARBOXYLIC ACID DERIVATIVES USEFUL AS PPAR MODULATORS | SmithKline Beecham Corporation (US) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008028118-A1 | 1H-INDOLE-2-CARBOXYLIC ACID DERIVATIVES USEFUL AS PPAR MODULATORS | SMITHKLINE BEECHAM CORPORAITON (US) | 2008-03-06 | — | — | WO | disclosed |