Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1384724 | 0.93 | KCNH2 (0.39) | F10KCNH2DGAT1ADORA2ATRPC3 | |
| SCHEMBL1385672 | 0.91 | F10 (0.41) | F10KCNH2DGAT1ADORA2ATRPC3 | |
| SCHEMBL1385505 | 0.89 | F10 (0.39) | F10KCNH2DGAT1ADORA2ATRPC3 | |
| SCHEMBL4385748 | 0.83 | F10 (0.53) | F10 | |
| SCHEMBL1385845 | 0.81 | KCNH2 (0.46) | F10KCNH2ACACB | |
| SCHEMBL1386823 | 0.80 | KCNH2 (0.52) | F10KCNH2 | |
| SCHEMBL1386449 | 0.79 | KCNH2 (0.39) | F10KCNH2ACACB | |
| SCHEMBL1386783 | 0.78 | KCNH2 (0.40) | F10KCNH2ACACB | |
| SCHEMBL1384406 | 0.77 | KCNH2 (0.45) | F10KCNH2 | |
| SCHEMBL1385080 | 0.77 | KCNH2 (0.45) | F10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |