SCHEMBL4400524

SCHEMBL4400524

[O]c1ccc2cc(Cl)ccc2c1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.43
TYMS P04818 1/20 0.39
F11 P03951 1/20 0.38
DAO P14920 2/20 0.35
ESR1 P03372 3/20 0.35
ESR2 Q92731 3/20 0.35
ALDH1A1 P00352 1/20 0.34
CHEK1 O14757 1/20 0.34
BCKDK O14874 1/20 0.34
MCL1 Q07820 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
AHR P35869 2/20 0.33
NR4A2 P43354 2/20 0.33
CMA1 P23946 1/20 0.33
F7 P08709 1/20 0.33
LTA4H P09960 1/20 0.33
F3 P13726 1/20 0.33
POLB P06746 1/20 0.33
MAOB P27338 1/20 0.33
PARP1 P09874 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6561368 0.78 CYP2A6 (0.57) CYP2A6TYMSF11DAOALDH1A1
SCHEMBL9244984 0.77 CYP2A6 (0.54) CYP2A6TYMSF11ESR1ESR2
SCHEMBL12205409 0.76 CYP2A6 (0.55) CYP2A6TYMSF11DAOALDH1A1
Hydrochloric Acid SCHEMBL29200220 0.76 CYP2A6 (0.52) CYP2A6TYMSF11ESR1ESR2
SCHEMBL15352196 0.74 CYP2A6 (0.48) CYP2A6TYMSF11DAOESR1
SCHEMBL3823814 0.74 TSHR (0.50) CYP2A6TYMSESR1ESR2ALDH1A1
SCHEMBL11057827 0.74 POLB (0.46) CYP2A6TYMSESR1ESR2ALDH1A1
SCHEMBL11141475 0.74 ESR1 (0.61) CYP2A6ESR1ESR2ALDH1A1
SCHEMBL29967129 0.74 TDP1 (0.53) CYP2A6TYMSF11ALDH1A1RXFP1
SCHEMBL4630777 0.73 CYP2A6 (0.60) CYP2A6ALDH1A1POLBMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090306376-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME MITSUI CHEMICALS, INC. (JP) 2009-12-10 US disclosed
US-20070054084-A1 Optical recording medium and compound used for the same MITSUI CHEMICALS, INC. (JP) 2007-03-08 US disclosed
EP-1672626-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED IN THE OPTICAL RECORDING MEDIUM Mitsui Chemicals, Inc. (JP) 2006-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306376-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME CACNA1B, KCNN4, KCNN2 CYP2A6 4014/4885TYMS 4075/4885F11 3202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.