SCHEMBL4401148

SCHEMBL4401148

Cc1ccc(/N=C(\c2ccccc2)c2ccc(-c3ccc(/C(=N/c4ccc(C)cc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 10/20 0.65
ESR1 P03372 9/20 0.53
CYP2D6 P10635 1/20 0.53
HIF1A Q16665 1/20 0.53
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
CTSL P07711 1/20 0.46
CTSB P07858 1/20 0.46
HTR3E A5X5Y0 2/20 0.44
HTR3B O95264 2/20 0.44
HTR3A P46098 2/20 0.44
HTR3D Q70Z44 2/20 0.44
HTR3C Q8WXA8 2/20 0.44
SLC22A2 O15244 1/20 0.44
SLC22A1 O15245 1/20 0.44
SLC22A3 O75751 1/20 0.44
PLAU P00749 1/20 0.44
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12336786 0.98 ESR2 (0.62) ESR2ESR1CYP2D6HIF1ACES2
SCHEMBL4401106 0.94 ESR2 (0.71) ESR2ESR1CYP2D6HIF1ACES2
SCHEMBL4402311 0.94 ESR2 (0.71) ESR2ESR1CYP2D6HIF1ACES2
SCHEMBL12336909 0.92 ESR2 (0.69) ESR2ESR1CYP2D6HIF1ACES2
SCHEMBL10910459 0.92 ESR2 (0.68) ESR2ESR1CYP2D6HIF1ACES2
SCHEMBL20198257 0.90 ESR2 (0.66) ESR2ESR1CYP2D6HIF1ACES2
SCHEMBL25693071 0.90 ESR2 (0.66) ESR2ESR1CYP2D6HIF1ACES2
SCHEMBL4403121 0.88 ESR2 (0.68) ESR2ESR1CYP2D6HIF1ACES2
SCHEMBL17928347 0.86 ESR2 (0.69) ESR2ESR1CYP2D6HIF1AHTR3E
SCHEMBL6932651 0.86 ESR2 (0.57) ESR2ESR1HTR3EHTR3BHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173276-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2012-05-08 US disclosed
US-8173276-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2012-05-08 US disclosed
US-20100102305-A1 MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF MERCK PATENT GMBH (DE) 2010-04-29 US disclosed
US-20100102305-A1 MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF MERCK PATENT GMBH (DE) 2010-04-29 US disclosed
US-7659540-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2010-02-09 US disclosed
US-7659540-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2010-02-09 US disclosed
US-20070080343-A1 New materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
US-20070080343-A1 New materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2007-04-12 US disclosed