SCHEMBL4401307

SCHEMBL4401307

CCCCOCCOCC[O]

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
CYP3A4 P08684 2/20 0.56
MEN1 O00255 1/20 0.46
THRB P10828 1/20 0.46
HTT P42858 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPT P10636 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.43
HPGD P15428 2/20 0.43
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39
ALDH1A1 P00352 3/20 0.39
CES2 O00748 2/20 0.38
RARB P10826 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
ATM Q13315 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14691204 1.00 TSHR (0.56) TSHRCYP3A4MEN1THRBHTT
SCHEMBL9651726 1.00 TSHR (0.56) TSHRCYP3A4MEN1THRBHTT
SCHEMBL430713 0.97
SCHEMBL21435850 0.94
SCHEMBL4390801 0.94 TSHR (0.52) TSHRCYP3A4MEN1THRBHTT
SCHEMBL4396859 0.94 TSHR (0.52) TSHRCYP3A4MEN1THRBHTT
SCHEMBL7418440 0.92 MEN1 (0.56) TSHRCYP3A4MEN1THRBHTT
SCHEMBL10958031 0.90 MEN1 (0.60) TSHRCYP3A4MEN1THRBHTT
SCHEMBL1402530 0.89
SCHEMBL4401732 0.89 TSHR (0.56) TSHRCYP3A4MEN1THRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218125-A1 AMIDOAMINE COMPOSITION AND ADHESIVE COMPOSITION CONTAINING THE SAME EVONIK OPERATIONS GMBH (DE) 2024-07-04 US claimed
EP-4337715-A1 AMIDOAMINE COMPOSITION AND ADHESIVE COMPOSITION CONTAININ THE SAME Evonik Operations GmbH (DE) 2024-03-20 EP claimed
US-9139688-B2 Copolymers of 3,4-dialkoxythiophenes and methods for making and devices SOLVAY USA, INC. (US) 2015-09-22 US claimed
WO-1995032736-A1 IMMOBILIZATION OF BIOLOGICALLY ACTIVE MATERIALS AND DIAGNOSTIC AGENTS IN CROSS-LINKED POLY(ORGANOPHOSPHAZENES) THE PENN STATE RESEARCH FOUNDATION (US) 1995-12-07 WO claimed
US-5446142-A Having one or more alkyl-or alkylenyloxy substituents; accuracy; high density and high speed recording; lasers; sensitivity; storage stability MITSUI TOATSU CHEMICALS, INC. (JP) 1995-08-29 US claimed
EP-0525880-A1 Catalytic alkylation process FMC CORPORATION (US) 1993-02-03 EP claimed
US-4940492-A Colorant mixtures containing isoquinoline derivatives, use thereof in printing inks, and novel isoquinoline derivatives BASF AKTIENGESELLSCHAFT (DE) 1990-07-10 US claimed
EP-0069294-B1 N-SUBSTITUTED 2 METHYLNAPHTHYL AMIDES, PROCESS FOR THEIR PREPARATION AND FUNGICIDES CONTAINING THEM BASF Aktiengesellschaft (DE) 1985-01-02 EP claimed
EP-0076382-A2 N-alkinyl-N-naphthyl amides, methods of making them and fungicides containing them BASF Aktiengesellschaft (DE) 1983-04-13 EP claimed
EP-0069294-A1 N-substituted 2 methylnaphthyl amides, process for their preparation and fungicides containing them BASF Aktiengesellschaft (DE) 1983-01-12 EP claimed
US-20240218125-A1 AMIDOAMINE COMPOSITION AND ADHESIVE COMPOSITION CONTAINING THE SAME EVONIK OPERATIONS GMBH (DE) 2024-07-04 US disclosed
CN-114423742-B Benzotriazole-based compound, light absorber and resin composition 三井化学株式会社 2024-05-28 CN disclosed
US-20240132675-A1 POLYMER HAVING METAL-OXYGEN-METAL BOND AS PRIMARY CHAIN, COMPOSITION THEREOF, SOLID MATERIAL AND PRODUCTION METHOD THEREOF, AND ELECTRONIC COMPONENT AND FIBER TORAY INDUSTRIES, INC. (JP) 2024-04-25 US disclosed
EP-4337715-A1 AMIDOAMINE COMPOSITION AND ADHESIVE COMPOSITION CONTAININ THE SAME Evonik Operations GmbH (DE) 2024-03-20 EP disclosed
CN-117466830-A Benzotriazole-based compound, light absorber and resin composition 三井化学株式会社 2024-01-30 CN disclosed
EP-0076382-A2 N-alkinyl-N-naphthyl amides, methods of making them and fungicides containing them BASF Aktiengesellschaft (DE) 1983-04-13 EP disclosed
EP-0069294-A1 N-substituted 2 methylnaphthyl amides, process for their preparation and fungicides containing them BASF Aktiengesellschaft (DE) 1983-01-12 EP disclosed
EP-0001870-B1 PROCESS FOR THE PREPARATION OF ORGANOTIN COMPOUNDS AKZO N.V. (NL) 1981-11-11 EP disclosed
US-4234501-A Process for the preparation of organotin compounds AKZO N.V. (NL) 1980-11-18 US disclosed
EP-0001870-A2 Process for the preparation of organotin compounds AKZO N.V. (NL) 1979-05-16 EP disclosed