Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | CCR1 | P32246 | 3/20 | 0.58 |
| ▸ | CCR5 | P51681 | 3/20 | 0.58 |
| ▸ | CCR8 | P51685 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ALPL | P05186 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | ALPG | P10696 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16806017 | 0.88 | KDM4E (0.50) | KDM4ECCR1CCR5CCR8SMN1; SMN2 | |
| SCHEMBL4406997 | 0.88 | TP53 (0.51) | KDM4ECCR1CCR5CCR8SMN1; SMN2 | |
| SCHEMBL4407010 | 0.88 | KDM4E (0.51) | KDM4ECCR1CCR5CCR8SMN1; SMN2 | |
| SCHEMBL4401765 | 0.88 | KMT2A (0.45) | KDM4ECCR1CCR8SMN1; SMN2TP53 | |
| SCHEMBL4401741 | 0.87 | KDM4E (0.50) | KDM4ECCR1CCR5CCR8SMN1; SMN2 | |
| SCHEMBL9228375 | 0.86 | CCR1 (0.49) | KDM4ECCR1CCR5CCR8SMN1; SMN2 | |
| SCHEMBL13962549 | 0.84 | CCR1 (0.52) | KDM4ECCR1CCR5CCR8SMN1; SMN2 | |
| SCHEMBL12731340 | 0.83 | KDM4E (0.67) | KDM4ECCR1CCR5CCR8SMN1; SMN2 | |
| SCHEMBL4404668 | 0.82 | MEN1 (0.53) | KDM4ETP53LMNAL3MBTL1TDP1 | |
| SCHEMBL10110964 | 0.82 | KDM4E (0.60) | KDM4ESMN1; SMN2TP53LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168307-B2 | Organic compound, charge transport material and organic electroluminescent device | PIONEER CORPORATION (JP) | 2012-05-01 | — | — | US | disclosed |