Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2672144 | 0.82 | HRH3 (0.40) | CTSDHDAC4HDAC1HDAC2HDAC6 | |
| SCHEMBL4402045 | 0.82 | HRH3 (0.40) | CTSDHDAC4HDAC1HDAC2HDAC6 | |
| SCHEMBL4399705 | 0.78 | HRH3 (0.34) | HRH3MLNR | |
| SCHEMBL19696332 | 0.78 | PRKCD (0.31) | CTSDHRH3 | |
| SCHEMBL13399582 | 0.72 | ABCB1 (0.36) | CTSDHDAC4HDAC1HRH3MLNR | |
| SCHEMBL13399581 | 0.72 | ABCB1 (0.36) | CTSDHDAC4HDAC1HRH3MLNR | |
| SCHEMBL6439632 | 0.72 | ABCB1 (0.36) | CTSDHDAC4HDAC1HRH3MLNR | |
| SCHEMBL13290575 | 0.72 | ABCB1 (0.36) | CTSDHDAC4HDAC1HRH3MLNR | |
| SCHEMBL18751776 | 0.72 | ABCB1 (0.36) | CTSDHDAC4HDAC1HRH3MLNR | |
| SCHEMBL13290576 | 0.72 | ABCB1 (0.36) | CTSDHDAC4HDAC1HRH3MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173809-B2 | Cysteine and cystine prodrugs to treat schizophrenia and reduce drug cravings | MARQUETTE UNIVERSITY (US) | 2012-05-08 | — | — | US | disclosed |