SCHEMBL4402212

SCHEMBL4402212

CCN(Cc1ccc(CN(CC)c2ccc(C)cc2)cc1)c1ccc(C)cc1

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.64
TSHR P16473 1/20 0.61
CNR2 P34972 17/20 0.60
CNR1 P21554 12/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22340785 1.00 CYP2C19 (0.64) CYP2C19TSHRCNR2CNR1
SCHEMBL15159234 0.96 CYP2C19 (0.60) CYP2C19TSHRCNR2CNR1
SCHEMBL4400864 0.94 CYP2C19 (0.58) CYP2C19TSHRCNR2CNR1
SCHEMBL12763737 0.94 CYP2C19 (0.58) CYP2C19TSHRCNR2CNR1
SCHEMBL12763739 0.91 CYP2C19 (0.82) CYP2C19TSHRCNR2CNR1
SCHEMBL12679019 0.91 CYP2C19 (0.55) CYP2C19TSHRCNR2CNR1
SCHEMBL27926523 0.91 CYP2C19 (0.55) CYP2C19TSHRCNR2CNR1
SCHEMBL11735496 0.90 CYP2C19 (0.81) CYP2C19TSHRCNR2CNR1
SCHEMBL11725374 0.90 TSHR (0.78) CYP2C19TSHRCNR2CNR1
SCHEMBL13778830 0.89 CYP2C19 (0.53) CYP2C19TSHRCNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11822286-B2 Process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2023-11-21 US disclosed
EP-3896524-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2021-10-20 EP disclosed
US-20210318629-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2021-10-14 US disclosed
US-9040215-B2 Amine compound, electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2015-05-26 US disclosed
US-9040215-B2 Amine compound, electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2015-05-26 US disclosed
EP-2549332-B1 Electrophotographic photoreceptor, image forming method and apparatus, and process cartridge RICOH CO LTD (JP) 2014-10-01 EP disclosed
US-20140234763-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2014-08-21 US disclosed
US-20130202994-A1 AMINE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-08-08 US disclosed
US-20130202994-A1 AMINE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-08-08 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-20100119964-A1 Electrophotographic photoreceptor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. 2010-05-13 US disclosed
US-20090324281-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2009-12-31 US disclosed
US-20090324281-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2009-12-31 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
EP-2078988-A2 Image forming apparatus and image forming method Ricoh Company, Ltd. (JP) 2009-07-15 EP disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed
US-20070287083-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE USING THE PHOTORECEPTOR RICOH COMPANY LTD. (JP) 2007-12-13 US disclosed
US-20070287083-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE USING THE PHOTORECEPTOR RICOH COMPANY LTD. (JP) 2007-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130202994-A1 AMINE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE ARL1, ATXN2L, AHR CYP2C19 849/4885TSHR 3163/4885CNR2 523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.