Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.54 |
| ▸ | CCR5 | P51681 | 1/20 | 0.54 |
| ▸ | CCR8 | P51685 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 5/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419277 | 0.80 | CCR1 (0.47) | CCR1CCR5CCR8HDAC6PTGS2 | |
| SCHEMBL9419246 | 0.80 | CCR1 (0.47) | CCR1CCR5CCR8HDAC6PTGS2 | |
| SCHEMBL9419266 | 0.78 | CCR1 (0.46) | CCR1CCR5CCR8HDAC6PTGS2 | |
| SCHEMBL9419245 | 0.77 | CCR1 (0.44) | CCR1CCR5CCR8HDAC6PTGS2 | |
| SCHEMBL4402368 | 0.77 | CCR1 (0.33) | CCR1CCR5CCR8HDAC6NOS3 | |
| SCHEMBL23667868 | 0.76 | CCR1 (0.52) | CCR1CCR5CCR8HDAC6PTGS2 | |
| SCHEMBL9419311 | 0.76 | CCR1 (0.43) | CCR1CCR5CCR8HDAC6PTGS2 | |
| SCHEMBL10303392 | 0.76 | FEN1 (0.45) | FEN1ALOX5APNPC1DHODHCYP11B1 | |
| SCHEMBL9326495 | 0.76 | HDAC6 (0.56) | CCR1CCR5CCR8HDAC6PTGS2 | |
| SCHEMBL17359276 | 0.75 | FEN1 (0.41) | PTGS2FEN1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140362335-A1 | POLYMER-DOPED VERTICALLY-ALIGNED NEMATIC LIQUID CRYSTALS | LC VISION, LLC (US) | 2014-12-11 | — | — | US | disclosed |
| US-20140362335-A1 | POLYMER-DOPED VERTICALLY-ALIGNED NEMATIC LIQUID CRYSTALS | LC VISION, LLC (US) | 2014-12-11 | — | — | US | disclosed |
| US-8834742-B2 | Polymer-doped vertically-aligned nematic liquid crystals | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-09-16 | — | — | US | disclosed |
| US-8834742-B2 | Polymer-doped vertically-aligned nematic liquid crystals | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120105791-A1 | POLYMER-DOPED VERTICALLY-ALIGNED NEMATIC LIQUID CRYSTALS | NATIONAL SCIENCE FOUNDATION | 2012-05-03 | — | — | US | disclosed |
| US-20120105791-A1 | POLYMER-DOPED VERTICALLY-ALIGNED NEMATIC LIQUID CRYSTALS | NATIONAL SCIENCE FOUNDATION | 2012-05-03 | — | — | US | disclosed |
| WO-2012016130-A2 | POLYMER-DOPED VERTICALLY-ALIGNED NEMATIC LIQUID CRYSTALS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-02-02 | — | — | WO | disclosed |
| EP-0363458-B1 | 2,3-DIFLUOROBENZENES | MERCK PATENT GMBH (DE) | 1994-08-03 | — | — | EP | disclosed |
| US-5087764-A | Deprotonation of a 1-substituted-2,3-difluorobenzene using an organometallic compound and reacting the reaction product with an electrophile | Merck Patent Gesellschaft mit beschrankter Hafung (DE) | 1992-02-11 | — | — | US | disclosed |
| EP-0363458-A1 | 2,3-DIFLUOROBENZENES. | MERCK PATENT GMBH (DE) | 1990-04-18 | — | — | EP | disclosed |
| WO-1989008629-A1 | PROCESS FOR PREPARING 2,3-DIFLUOROBENZENES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |