Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 19/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4404736 | 0.96 | FGFR4 (0.50) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL4412853 | 0.94 | FGFR4 (0.56) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL4406873 | 0.93 | FGFR4 (0.52) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL4412508 | 0.92 | FGFR4 (0.55) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL4409361 | 0.91 | FGFR4 (0.54) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL4410341 | 0.91 | FGFR4 (0.52) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL4398331 | 0.90 | FGFR4 (0.47) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL4407910 | 0.89 | FGFR4 (0.53) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL4405628 | 0.89 | FGFR4 (0.52) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL4403231 | 0.88 | FGFR4 (0.59) | FGFR4FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549651-B1 | PYRIMIDOPYRIMIDONES AS KINASE INHIBITORS | WARNER LAMBERT CO (US) | 2009-12-23 | — | — | EP | disclosed |