⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4401922 | 0.90 | — | — | |
| SCHEMBL4401924 | 0.88 | — | — | |
| SCHEMBL13564144 | 0.73 | — | — | |
| SCHEMBL19302820 | 0.70 | — | — | |
| SCHEMBL28745214 | 0.67 | — | — | |
| SCHEMBL9613600 | 0.65 | — | — | |
| SCHEMBL14620892 | 0.65 | — | — | |
| SCHEMBL15048839 | 0.65 | TYMP (0.40) | — | |
| SCHEMBL604266 | 0.65 | TYMP (0.40) | — | |
| SCHEMBL10440472 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393919-A1 | LSD1 MODULATORS | Exscientia Al Limited (GB) | 2024-07-03 | — | — | EP | disclosed |
| CN-118284093-A | Light emitting device and electronic apparatus including the same | 三星电子株式会社 | 2024-07-02 | — | — | CN | disclosed |
| CN-118284092-A | Light emitting device and electronic apparatus including the same | 三星电子株式会社 | 2024-07-02 | — | — | CN | disclosed |
| EP-3442947-B1 | AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS AS EHMT1 AND EHMT2 INHIBITORS | EPIZYME INC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-20210198277-A1 | AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS | Epizyme, Inc. | 2021-07-01 | — | — | US | disclosed |
| WO-2020108538-A1 | RORγ INHIBITOR HAVING SULFONYL STRUCTURE | 正大天晴药业集团股份有限公司 | 2020-06-04 | — | — | WO | disclosed |
| CN-104768932-B | The heteroaryl inhibitors of PDE4 | 泰特拉探索合伙有限责任公司 | 2018-08-07 | — | — | CN | disclosed |
| CN-105008378-B | The manufacturing method of cross-coupling catalysts and aromatic compound | 北兴化学工业株式会社 | 2018-05-18 | — | — | CN | disclosed |
| WO-2018013613-A1 | C17, C20, AND C21 SUBSTITUTED NEUROACTIVE STEROIDS AND THEIR METHODS OF USE | SAGE THERAPEUTICS, INC. (US) | 2018-01-18 | — | — | WO | disclosed |
| US-20170355712-A1 | AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS | Epizyme, Inc. | 2017-12-14 | — | — | US | disclosed |
| CN-103313981-A | 2-methoxy-pyridin-4-yl derivatives | ACTELION PHARMACEUTICALS LTD | 2013-09-18 | — | — | CN | disclosed |
| EP-2364306-B1 | Pyridine and pyrimidine derivatives as phosphodiesterase 10 inhibitors | AMGEN INC (US) | 2013-04-24 | — | — | EP | disclosed |
| WO-2012098505-A1 | 2-METHOXY-PYRIDIN-4-YL DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-07-26 | — | — | WO | disclosed |
| US-8178552-B2 | 7-Azaindole derivatives and their use in the inhibition of c-Jun N-terminal kinase | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-8178552-B2 | 7-Azaindole derivatives and their use in the inhibition of c-Jun N-terminal kinase | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| WO-2010031750-A1 | ORGANIC COMPOUNDS FOR APPLICATIONS IN BACTERIAL INFECTIONS TREATMENT | NOVARTIS AG (CH) | 2010-03-25 | — | — | WO | disclosed |
| US-20100069354-A1 | 7-AZAINDOLE DERIVATIVES AND THEIR USE IN THE INHIBITION OF C-JUN N-TERMINAL KINASE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20100069354-A1 | 7-AZAINDOLE DERIVATIVES AND THEIR USE IN THE INHIBITION OF C-JUN N-TERMINAL KINASE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20090159130-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2009-06-25 | — | — | US | disclosed |
| WO-2008095944-A1 | 7-AZAINDOLE DERIVATIVES AND THEIR USE IN THE INHIBITION OF C-JUN N-TERMINAL KINASE | EISAI R&D MANAGEMENT CO. LTD. (JP) | 2008-08-14 | — | — | WO | disclosed |