SCHEMBL440403

SCHEMBL440403

OC[C@H]1O[C@@H](c2ccccc2O)[C@H](O)[C@@H](O)[C@H]1O

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 11/20 0.59
EPHX2 P34913 2/20 0.47
PYGL P06737 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15284566 1.00 SLC5A2 (0.59) SLC5A2EPHX2PYGL
SCHEMBL6542524 1.00 SLC5A2 (0.59) SLC5A2EPHX2PYGL
SCHEMBL28445368 1.00 SLC5A2 (0.59) SLC5A2EPHX2PYGL
SCHEMBL15271703 1.00 SLC5A2 (0.59) SLC5A2EPHX2PYGL
SCHEMBL28433449 1.00 SLC5A2 (0.59) SLC5A2EPHX2PYGL
SCHEMBL2917657 0.98 SLC5A2 (0.57) SLC5A2EPHX2PYGL
SCHEMBL15284629 0.84 SLC5A2 (0.48) SLC5A2EPHX2
SCHEMBL17941667 0.82 SLC5A2 (0.62) SLC5A2
SCHEMBL17941664 0.82 SLC5A2 (0.62) SLC5A2
SCHEMBL6673371 0.80 SLC5A2 (0.50) SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1421385-B1 GENETIC CONSTRUCT INTRACELLULAR MONITORING SYSTEM DISCOVERX CORP (US) 2016-06-29 EP disclosed
EP-1766397-B1 ANALYSIS OF INTRACELLULAR MODIFICATIONS DISCOVERX CORP (US) 2016-03-09 EP disclosed
US-8101373-B2 β-galactosidase donor fragments DISCOVERX CORPORATION (US) 2012-01-24 US disclosed
US-7608415-B2 Analysis of intracellular modifications DISCOVERX CORPORATION (US) 2009-10-27 US disclosed
US-20090098588-A1 BETA GALACTOSIDASE DONOR FRAGMENTS DISCOVERX CORPORATION (US) 2009-04-16 US disclosed
EP-1766397-A4 ANALYSIS OF INTRACELLULAR MODIFICATIONS DISCOVERX INC (US) 2009-02-25 EP disclosed
US-7479377-B2 Genetic construct intracellular monitoring system DISCOVERX CORPORATION (US) 2009-01-20 US disclosed
EP-1474526-B1 ENZYME ACTIVATION PROTEASE ASSAY DISCOVERX INC (US) 2008-06-25 EP disclosed
US-7256011-B2 Enzyme activation protease assay DISCOVERX INC. (US) 2007-08-14 US disclosed
US-7202043-B2 Detecting cell membrane protein endocytosis DISCOVER CORPORATION (US) 2007-04-10 US disclosed
WO-2006004936-A2 ANALYSIS OF INTRACELLULAR MODIFICATIONS DISCOVERX, INC. (US) 2006-01-12 WO disclosed
EP-1474526-A4 ENZYME ACTIVATION PROTEASE ASSAY DISCOVERX INC (US) 2005-08-24 EP disclosed
EP-1551965-A2 SHORT ENZYME DONOR FRAGMENT Discoverx, Inc. (US) 2005-07-13 EP disclosed
EP-1474526-A2 ENZYME ACTIVATION PROTEASE ASSAY Discoverx, Inc. (US) 2004-11-10 EP disclosed
US-20040137480-A1 Monitoring intracellular proteins DISCOVERX, INC. 2004-07-15 US disclosed
US-20030219848-A1 Short enzyme donor fragment EUROFINS DISCOVERX CORPORATION 2003-11-27 US disclosed
WO-2003093786-A2 SHORT ENZYME DONOR FRAGMENT DISCOVERX, INC. (US) 2003-11-13 WO disclosed
US-20030170770-A1 Enzyme activation protease assay EUROFINS DISCOVERX CORPORATION 2003-09-11 US disclosed
WO-2003065004-A2 ENZYME ACTIVATION PROTEASE ASSAY DISCOVERX, INC. (US) 2003-08-07 WO disclosed
US-20030092070-A1 Genetic construct intracellular monitoring system EUROFINS DISCOVERX CORPORATION 2003-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030219848-A1 Short enzyme donor fragment GLB1, GBA3, GLA SLC5A2 2571/4885EPHX2 3782/4885PYGL 85/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.