Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 20/20 | 0.64 |
| ▸ | CPT2 | P23786 | 9/20 | 0.64 |
| ▸ | CPT1B | Q92523 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3548728 | 0.89 | CPT1A (0.66) | CPT1ACPT2CPT1B | |
| SCHEMBL3547504 | 0.84 | CPT1A (0.76) | CPT1ACPT2CPT1B | |
| SCHEMBL3547509 | 0.84 | CPT1A (0.76) | CPT1ACPT2CPT1B | |
| SCHEMBL3558625 | 0.83 | CPT1A (0.77) | CPT1ACPT2CPT1B | |
| SCHEMBL3554922 | 0.81 | CPT1A (0.79) | CPT1ACPT2CPT1B | |
| SCHEMBL3556283 | 0.81 | CPT1A (0.66) | CPT1ACPT2CPT1B | |
| SCHEMBL4399877 | 0.80 | CPT1A (0.67) | CPT1ACPT2CPT1B | |
| SCHEMBL4399874 | 0.80 | CPT1A (0.67) | CPT1ACPT2CPT1B | |
| SCHEMBL3556573 | 0.80 | CPT1A (0.77) | CPT1ACPT2CPT1B | |
| SCHEMBL3547972 | 0.80 | CPT1A (0.80) | CPT1ACPT2CPT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959951-B1 | HETEROARYL SUBSTITUTED PIPERIDINE DERIVATIVES AS L-CPT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-12-23 | — | — | EP | claimed |