Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540936 | 0.88 | FABP6 (0.45) | FABP6ABL1MEN1ALDH1A1KMT2A | |
| SCHEMBL725577 | 0.83 | FABP6 (0.50) | FABP6ABL1MEN1ALDH1A1KMT2A | |
| SCHEMBL11148656 | 0.81 | HCRTR1 (0.53) | MEN1ALDH1A1KMT2AMMP2MMP13 | |
| SCHEMBL1870891 | 0.81 | FABP6 (0.55) | FABP6ABL1MEN1ALDH1A1KMT2A | |
| SCHEMBL22121440 | 0.81 | FABP6 (0.51) | FABP6ABL1MEN1ALDH1A1KMT2A | |
| SCHEMBL3607728 | 0.80 | FABP6 (0.48) | FABP6ABL1MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL4682527 | 0.80 | FABP6 (0.54) | FABP6ABL1MEN1ALDH1A1KMT2A | |
| SCHEMBL17747823 | 0.79 | FABP6 (0.47) | FABP6ABL1MEN1ALDH1A1KMT2A | |
| SCHEMBL1202574 | 0.79 | KDM4E (0.50) | FABP6ABL1MEN1ALDH1A1KMT2A | |
| Bromide SCHEMBL214290 | 0.78 | KDM4E (0.49) | FABP6ABL1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012056372-A1 | N1/N2-LACTAM ACETYL-CoA CARBOXYLASE INHIBITORS | PFIZER INC. (US) | 2012-05-03 | — | — | WO | disclosed |
| EP-0091794-B1 | PROCESS FOR PREPARING 1.6-DISUBSTITUTED 2-AMINOBENZIMIDAZOLES | ELI LILLY AND COMPANY (US) | 1988-11-30 | — | — | EP | disclosed |
| US-4434288-A | Preparation of substituted 1-thiazinyl or 1-thiazolyl-2-aminobenzimidazoles | ELI LILLY AND COMPANY (US) | 1984-02-28 | — | — | US | disclosed |
| EP-0091794-A1 | Process for preparing 1.6-disubstituted 2-aminobenzimidazoles | ELI LILLY AND COMPANY (US) | 1983-10-19 | — | — | EP | disclosed |