⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597124 | 0.75 | — | — | |
| Bromide SCHEMBL27092037 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL5967571 | 0.73 | — | — | |
| SCHEMBL22551299 | 0.72 | CYP2C19 (0.60) | — | |
| SCHEMBL6444227 | 0.72 | — | — | |
| SCHEMBL9129718 | 0.71 | — | — | |
| SCHEMBL10583845 | 0.69 | — | — | |
| SCHEMBL10403366 | 0.69 | — | — | |
| SCHEMBL10403365 | 0.69 | — | — | |
| SCHEMBL15791167 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745857-A | Orally-administered active oxygen-responsive thioester compound, and synthesis method and application thereof | 中国医学科学院放射医学研究所 | 2023-03-07 | — | — | CN | disclosed |
| US-8822442-B2 | Somatostatin-dopamine chimeric analogs | IPSEN PHARMA S.A.S. (FR) | 2014-09-02 | — | — | US | disclosed |
| US-8324386-B2 | Somatostatin-dopamine chimeric analogs | IPSEN PHARMA S.A.S. (FR) | 2012-12-04 | — | — | US | disclosed |
| US-8178651-B2 | Somatostatin-dopamine chimeric analogs | IPSEN PHARMA, S.A.S. (FR) | 2012-05-15 | — | — | US | disclosed |
| US-20100179304-A1 | Somatostatin-Dopamine Chimeric analogs | IPSEN PHARMA S.A.S. (FR) | 2010-07-15 | — | — | US | disclosed |
| US-20090275501-A1 | Somatostatin-dopamine chimeric analogs | IPSEN PHARMA S.A.S. (FR) | 2009-11-05 | — | — | US | disclosed |
| US-7579435-B2 | Somatostatin-dopamine chimeric analogs | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2009-08-25 | — | — | US | disclosed |
| US-7572883-B2 | Somatostatin-dopamine chimeric analogs | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2009-08-11 | — | — | US | disclosed |
| EP-0716693-A1 | METHOD AND REAGENT FOR INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | RIBOZYME PHARMACEUTICALS, INC. (US) | 1996-06-19 | — | — | EP | disclosed |
| WO-1995004818-A1 | METHOD AND REAGENT FOR INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | RIBOZYME PHARMACEUTICALS, INC. (US) | 1995-02-16 | — | — | WO | disclosed |