Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 16/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 14/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8269375 | 0.83 | DPP4 (0.52) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL4404837 | 0.82 | DPP4 (0.49) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL2701613 | 0.81 | DPP4 (0.49) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL2701610 | 0.81 | DPP4 (0.49) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL2703946 | 0.80 | DPP4 (0.55) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL8268801 | 0.77 | DPP4 (0.44) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL4403942 | 0.75 | DPP4 (0.53) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL2703110 | 0.74 | DPP4 (0.53) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL4403323 | 0.74 | DPP4 (0.53) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL8268741 | 0.74 | DPP4 (0.53) | DPP4DPP8DPP9CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888589-B1 | PYRROLOPYRIDINE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND METHODS | BRISTOL MYERS SQUIBB CO (US) | 2012-05-09 | — | — | EP | disclosed |