Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 20/20 | 0.63 |
| ▸ | FNTB | P49356 | 19/20 | 0.63 |
| ▸ | PGGT1B | P53609 | 8/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2676603 | 1.00 | FNTA (0.63) | FNTAFNTBPGGT1BKCNH2 | |
| Hydrochloric Acid SCHEMBL8590479 | 0.99 | FNTA (0.62) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL5583314 | 0.94 | FNTA (0.72) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL28013379 | 0.91 | FNTA (0.55) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL445938 | 0.83 | FNTA (0.88) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL445940 | 0.83 | FNTA (0.88) | FNTAFNTBPGGT1BKCNH2 | |
| Hydrochloric Acid SCHEMBL9083203 | 0.83 | FNTA (0.87) | FNTAFNTBPGGT1BKCNH2 | |
| Hydrochloric Acid SCHEMBL9083210 | 0.83 | FNTA (0.87) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL6220060 | 0.78 | FNTA (0.86) | FNTAFNTBPGGT1B | |
| SCHEMBL31472029 | 0.77 | FNTA (1.00) | FNTAFNTBPGGT1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132198-A1 | SOLID FORMS OF A RAF KINASE INHIBITOR | Novartis Ag (CH) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008140850-A1 | SOLID FORMS OF A RAF KINASE INHIBITOR | NOVARTIS AG (CH) | 2008-11-20 | — | — | WO | disclosed |
| WO-2005097770-A1 | NOVEL HYDROXAMATES AS THERAPEUTIC AGENTS | PHARMACYCLICS, INC. (US) | 2005-10-20 | — | — | WO | disclosed |