SCHEMBL4405099

SCHEMBL4405099

CC(C)n1nnc(C(Cl)(Cl)Cl)n1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4406640 0.83
SCHEMBL4403739 0.82 TOP2A (0.31) NPC1RAB9A
SCHEMBL14417140 0.78 NPC1 (0.30) NPC1RAB9A
SCHEMBL4407966 0.78 TLR7 (0.34) NPC1RAB9A
SCHEMBL4404399 0.71
SCHEMBL4405779 0.70
SCHEMBL4415072 0.70
SCHEMBL4405977 0.70 TSHR (0.31)
SCHEMBL4407794 0.70 SMN1; SMN2 (0.39) NPC1RAB9A
SCHEMBL4416610 0.69 TRPV1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859782-B1 Composition for coloring and/or lightening human hair comprising tetrazoles HENKEL AG & CO KGAA (DE) 2009-12-30 EP disclosed
EP-1859782-A1 Composition for coloring and/or lightening human hair comprising tetrazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed