SCHEMBL440610

SCHEMBL440610

NC1(Cl)C=CC=CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11117994 0.71
SCHEMBL872395 0.67
SCHEMBL7870298 0.67
SCHEMBL9250018 0.67
SCHEMBL5269335 0.67
SCHEMBL9696000 0.67
SCHEMBL2973243 0.67
SCHEMBL17608785 0.67
SCHEMBL20163151 0.67
SCHEMBL14361189 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1910152-B Process for the manufacture of 2,3-dichloropyridine DU PONT 2010-07-21 CN claimed
CN-1910152-A Process for the manufacture of 2,3-dichloropyridine DU PONT (US) 2007-02-07 CN claimed
CN-119390645-A Dehalogenation method for reducing N heteroaryl halide by using hydrosilane 浙江科技大学 2025-02-07 CN disclosed
EP-3645531-A1 THIAZOLE COMPOUNDS USEFUL AS PRMT5 INHIBITORS Bayer Aktiengesellschaft (DE) 2020-05-06 EP disclosed
US-20200123147-A1 THIAZOLE COMPOUNDS USEFUL AS PRMT5 INHIBITORS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2020-04-23 US disclosed
WO-2019002074-A1 THIAZOLE COMPOUNDS USEFUL AS PRMT5 INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 2019-01-03 WO disclosed
US-9112094-B2 Copper tin sulfide and copper zinc tin sulfide ink compositions E I DU PONT DE NEMOURS AND COMPANY (US) 2015-08-18 US disclosed
US-9105796-B2 CZTS/Se precursor inks and methods for preparing CZTS/Se thin films and CZTS/Se-based photovoltaic cells E I DU PONT DE NEMOURS AND COMPANY (US) 2015-08-11 US disclosed
US-20150118144-A1 DISPERSIBLE METAL CHALCOGENIDE NANOPARTICLES E I DU PONT NEMOURS AND COMPANY (US) 2015-04-30 US disclosed
WO-2015023958-A1 TOLL-LIKE RECEPTOR AGONISTS THE UNIVERSITY OF KANSAS (US) 2015-02-19 WO disclosed
US-20140144500-A1 SEMICONDUCTOR INKS FILMS, COATED SUBSTRATES AND METHODS OF PREPARATION E I DU PONT DE NEMOURS AND COMPANY (US) 2014-05-29 US disclosed
EP-1358161-A2 N-PYRIDYL CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Amgen Inc. (US) 2003-11-05 EP disclosed
US-6562844-B2 Attaching an olefin to a solid support; oxidizing the olefin to provide an epoxide functionality; opening the epoxide with an amine to form an amino alcohol; cyclizing the amino alcohol using a phosgene equivalent PHARMACIA & UPJOHN COMPANY 2003-05-13 US disclosed
US-6531470-B1 Antimicrobial compounds PHARMACIA & UPJOHN COMPANY 2003-03-11 US disclosed
WO-2002055501-A2 N-PYRIDYL CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AMGEN INC (US) 2002-07-18 WO disclosed
US-6239152-B1 Oxazolidinone combinatorial libraries, compositions and methods of preparation PHARMACIA & UPJOHN COMPANY 2001-05-29 US disclosed
CN-1288462-A Oxazolidinone combinatorial libraries, compositions and method of prepn. UPJOHN CO (US) 2001-03-21 CN disclosed
EP-0410148-A1 Novel 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-ones and thiones and their use in the prevention or treatment of AIDS Boehringer Ingelheim Pharmaceuticals Inc. (US) 1991-01-30 EP disclosed
EP-0288201-A1 Process for the preparation of benzodiazepines A.H. ROBINS COMPANY, INCORPORATED (US) 1988-10-26 EP disclosed
US-4749788-A Process for the preparation of aryl-pyrido(1,4) benzodiazepines A. H. ROBINS COMPANY, INCORPORATED (US) 1988-06-07 US disclosed