Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12417673 | 0.94 | MEN1 (0.48) | MEN1KMT2AMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL19127326 | 0.94 | MEN1 (0.48) | MEN1KMT2AMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL16420207 | 0.94 | MEN1 (0.48) | MEN1KMT2AMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL12417668 | 0.94 | MEN1 (0.48) | MEN1KMT2AMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL19127441 | 0.94 | MEN1 (0.48) | MEN1KMT2AMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL13590559 | 0.94 | MEN1 (0.48) | MEN1KMT2AMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL15223770 | 0.94 | MEN1 (0.48) | MEN1KMT2AMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL6002499 | 0.94 | MEN1 (0.48) | MEN1KMT2AMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL423611 | 0.94 | MEN1 (0.48) | MEN1KMT2AMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL18467815 | 0.94 | MEN1 (0.48) | MEN1KMT2AMTNR1AMTNR1BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173843-B2 | Amphiphilic derivatives of α-C-phenyl-N-tert-butylnitrone | TS PHARMA (FR) | 2012-05-08 | — | — | US | disclosed |
| US-7655251-B2 | Amphiphilic derivatives of α-C-phenyl-N-tert-butylnitrone | TS PHARMA (FR) | 2010-02-02 | — | — | US | disclosed |