Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403673 | 0.95 | TRPV1 (0.37) | KMT2ARECQLTRPV1 | |
| SCHEMBL4413458 | 0.93 | TRPV1 (0.39) | TRPV1 | |
| SCHEMBL4407372 | 0.89 | RECQL (0.45) | KMT2ARAB9AALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL4407234 | 0.81 | TRPV1 (0.38) | RAB9ASMN1; SMN2RECQLNPC1CNR1 | |
| SCHEMBL4414619 | 0.81 | KMT2A (0.39) | KMT2ARAB9AALDH1A1F2MAPT | |
| SCHEMBL4409043 | 0.79 | KMT2A (0.38) | KMT2ARAB9AMEN1NPC1TSHR | |
| SCHEMBL4414593 | 0.79 | KMT2A (0.38) | KMT2ARAB9AALDH1A1F2MAPT | |
| SCHEMBL4405663 | 0.78 | KMT2A (0.40) | KMT2AMEN1 | |
| SCHEMBL4408960 | 0.77 | TRPV1 (0.53) | CNR1CNR2TRPV1 | |
| SCHEMBL4405063 | 0.76 | TRPV1 (0.39) | KMT2ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |