Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,4-Butanediol SCHEMBL7850531 | 0.97 | SMN1; SMN2 (0.35) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| Ethylene Glycol SCHEMBL2955063 | 0.83 | — | — | |
| Ethylene Glycol SCHEMBL7850509 | 0.80 | TSHR (0.36) | TSHR | |
| Ethylene Glycol SCHEMBL7848447 | 0.75 | TSHR (0.32) | TSHR | |
| 1,6-Hexanediol SCHEMBL29249024 | 0.73 | TSHR (0.50) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| 1,6-Hexanediol SCHEMBL22977579 | 0.73 | TSHR (0.50) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| 1,6-Hexanediol SCHEMBL21353993 | 0.73 | TSHR (0.50) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| Propene SCHEMBL28542606 | 0.73 | TSHR (0.50) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| 1,4-Butanediol SCHEMBL1538425 | 0.72 | SMN1; SMN2 (0.41) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| 1,4-Butanediol SCHEMBL21065566 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286823-B1 | OPHTHALMIC LENSES AND COMPOSITIONS, AND METHODS FOR PRODUCING SAME | COOPERVISION INT HOLDING CO LP (BB) | 2009-06-17 | — | — | EP | disclosed |
| US-7262232-B2 | Ophthalmic lenses and compositions and methods for producing same | COOPERVISION, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-6992118-B2 | Ophthalmic lenses and compositions and methods for producing same | COOPER VISION INC. (US) | 2006-01-31 | — | — | US | disclosed |
| US-20050191335-A1 | Ophthalmic lenses and compositions and methods for producing same | COOPERVISION INC. (US) | 2005-09-01 | — | — | US | disclosed |
| EP-1286823-A4 | OPHTHALMIC LENSES AND COMPOSITIONS, AND METHODS FOR PRODUCING SAME | OCULAR SCIENCES INC (US) | 2005-01-12 | — | — | EP | disclosed |
| US-20040046932-A1 | Ophthalmic lenses and compositions and methods for producing same | OCULAR SCIENCES, INC. | 2004-03-11 | — | — | US | disclosed |
| US-6617373-B2 | First crosslinked polymer material which is water swellable, and a second polymeric material physically imobilized by the first | OCULAR SCIENCES, INC. | 2003-09-09 | — | — | US | disclosed |
| EP-1286823-A1 | OPHTHALMIC LENSES AND COMPOSITIONS, AND METHODS FOR PRODUCING SAME | Ocular Sciences Inc. (US) | 2003-03-05 | — | — | EP | disclosed |
| US-20020091175-A1 | Ophthalmic lenses and compositions and methods for producing same | OCULAR SCIENCES, INC. | 2002-07-11 | — | — | US | disclosed |
| WO-2001078971-A1 | OPHTHALMIC LENSES AND COMPOSITIONS, AND METHODS FOR PRODUCING SAME | OCULAR SCIENCES, INC. (US) | 2001-10-25 | — | — | WO | disclosed |