Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR10 | P46092 | 12/20 | 0.68 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336027 | 0.87 | CCR10 (0.67) | CCR10F10PLAUF2 | |
| SCHEMBL12126947 | 0.87 | CCR10 (0.67) | CCR10F10PLAUF2 | |
| SCHEMBL1311446 | 0.86 | CCR10 (0.70) | CCR10F2 | |
| SCHEMBL1038712 | 0.85 | CCR10 (0.69) | CCR10F2 | |
| SCHEMBL1338000 | 0.85 | CCR10 (0.65) | CCR10F10PLAUF2 | |
| SCHEMBL1337926 | 0.85 | CCR10 (0.67) | CCR10F10PLAUF2 | |
| SCHEMBL1337985 | 0.85 | CCR10 (0.67) | CCR10F10PLAUF2 | |
| SCHEMBL1337823 | 0.85 | CCR10 (0.67) | CCR10F10PLAUF2 | |
| SCHEMBL1337632 | 0.84 | CCR10 (0.66) | CCR10F10PLAUF2 | |
| SCHEMBL1338128 | 0.84 | CCR10 (0.66) | CCR10F10PLAUF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2294051-B1 | ALPHA-SUBSTITUTED N-SULFONYL GYLCINE AMIDES ANTAGONISTS OF CCR10, COMPOSITIONS CONTAINING THE SAME AND METHODS FOR USING THEM | BOEHRINGER INGELHEIM INT (DE) | 2014-08-13 | — | — | EP | disclosed |
| WO-2009142984-A1 | ALPHA-SUBSTITUTED N-SULFONYL GYLCINE AMIDES ANTAGONISTS OF CCR10, COMPOSITIONS CONTAINING THE SAME AND METHODS FOR USING THEM | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-26 | — | — | WO | disclosed |