Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.58 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.34 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL4409187 | 1.00 | SLC7A5 (0.58) | SLC7A5SLC1A1SLC1A3SLC1A2USP2 | |
| Threonine SCHEMBL27468644 | 0.94 | USP2 (0.47) | SLC7A5SLC1A1SLC1A3SLC1A2USP2 | |
| Threonine SCHEMBL9139658 | 0.94 | USP2 (0.47) | SLC7A5SLC1A1SLC1A3SLC1A2USP2 | |
| Threonine SCHEMBL7730685 | 0.94 | USP2 (0.47) | SLC7A5SLC1A1SLC1A3SLC1A2USP2 | |
| Threonine SCHEMBL103941 | 0.94 | USP2 (0.47) | SLC7A5SLC1A1SLC1A3SLC1A2USP2 | |
| Threonine SCHEMBL9139632 | 0.94 | USP2 (0.47) | SLC7A5SLC1A1SLC1A3SLC1A2USP2 | |
| Threonine SCHEMBL1537268 | 0.94 | USP2 (0.47) | SLC7A5SLC1A1SLC1A3SLC1A2USP2 | |
| Threonine SCHEMBL5710205 | 0.94 | USP2 (0.47) | SLC7A5SLC1A1SLC1A3SLC1A2USP2 | |
| Threonine SCHEMBL1537265 | 0.94 | USP2 (0.47) | SLC7A5SLC1A1SLC1A3SLC1A2USP2 | |
| Threonine SCHEMBL103943 | 0.94 | USP2 (0.47) | SLC7A5SLC1A1SLC1A3SLC1A2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210257-A4 | PROTEIN WHICH IS CHARACTERISTIC OF RHEUMATOID ARTHRITIS. | HURWITZ CHARLES (US) | 1988-01-20 | — | — | EP | claimed |
| EP-0210257-A1 | PROTEIN WHICH IS CHARACTERISTIC OF RHEUMATOID ARTHRITIS | HURWITZ, Charles (US) | 1987-02-04 | — | — | EP | claimed |
| WO-1986004588-A1 | PROTEIN WHICH IS CHARACTERISTIC OF RHEUMATOID ARTHRITIS | HURWITZ CHARLES (US) | 1986-08-14 | — | — | WO | claimed |
| EP-2042601-A1 | Novel variant EGIII-like cellulase compositions | Genencor International, Inc. (US) | 2009-04-01 | — | — | EP | disclosed |
| EP-1305431-A2 | MUTANT TRICHODERMA REESEI EGIII CELLULASES, DNA ENCODING SUCH EGIII COMPOSITIONS AND METHODS FOR OBTAINING SAME | GENENCOR INTERNATIONAL, INC. (US) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002012464-A2 | MUTANT TRICHODERMA REESEI EGIII CELLULASES DNA ENCODING SUCH EGIII COMPOSITIONS AND METHODS FOR OBTAINING SAME | GENENCOR INTERNATIONAL, INC. (US) | 2002-02-14 | — | — | WO | disclosed |