⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020883 | 0.96 | — | — | |
| SCHEMBL394179 | 0.96 | — | — | |
| SCHEMBL2813902 | 0.92 | — | — | |
| SCHEMBL8335338 | 0.89 | — | — | |
| SCHEMBL258395 | 0.88 | — | — | |
| SCHEMBL11416603 | 0.80 | — | — | |
| SCHEMBL18602568 | 0.79 | NPC1 (0.34) | — | |
| SCHEMBL9713560 | 0.77 | — | — | |
| SCHEMBL20382856 | 0.76 | — | — | |
| SCHEMBL22506808 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604983-B2 | Herbicidal 3-(2-benzyloxyphenyl)-2,4-dihydroxy-1,8-naphthyridine derivatives | SYNGENTA LIMITED (GB) | 2017-03-28 | — | — | US | disclosed |
| EP-2417143-B1 | SYNTHESIS OF 2'-O-FUCOSYLLACTOSE | GLYCOM AS (DK) | 2016-12-21 | — | — | EP | disclosed |
| US-20160304509-A1 | HERBICIDAL 3-(2-BENZYLOXYPHENYL)-2,4-DIHYDROXY-1,8-NAPHTHYRIDINE DERIVATIVES | SYNGENTA LIMITED (GB) | 2016-10-20 | — | — | US | disclosed |
| US-9126987-B2 | Inhibitors of glutaminyl cyclase | PROBIODRUG AG (DE) | 2015-09-08 | — | — | US | disclosed |
| US-9012625-B2 | Method for the synthesis of a trisaccharide | GLYCOM A/S (DK) | 2015-04-21 | — | — | US | disclosed |
| US-20130131334-A1 | METHOD FOR THE SYNTHESIS OF A TRISACCHARIDE | Glycom A/S Danmarks Tekniske Universitet (DK) | 2013-05-23 | — | — | US | disclosed |
| EP-2091948-B1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2012-04-18 | — | — | EP | disclosed |
| US-20120065219-A1 | SPIROCYCLIC AZAADAMANTANE DERIVATIVES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2012-03-15 | — | — | US | disclosed |
| EP-2417143-A1 | SYNTHESIS OF 2'-O-FUCOSYLLACTOSE | Glycom A/S (DK) | 2012-02-15 | — | — | EP | disclosed |
| US-8076350-B2 | 3H-(4's)-1'-azaspiro[benzofuran-2,4']-tricyclo[3.3.1.13,7]decane; for therapy of memory disorder, cognitive disorder, neurodegeneration, and neurodevelopmental disorder; attention deficit disorder, attention deficit hyperactivity disorder (ADHD), Alzheimer's disease (AD), mild cognitive impairment | ABBOTT LABORATORIES (US) | 2011-12-13 | — | — | US | disclosed |
| US-7442792-B2 | halogenation of pyrazolo[1,5-a][1,3,5]triazin-4-ol's, with phosphorus oxyhalides, then dehalogenation and amination to yield dimethylpyrazolo[1,5-a][1,3,5]triazin-4-amine's, used as corticotropin releasing factor (CRF) receptor antagonists; anxiolytic agents; antidepressants | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2008-10-28 | — | — | US | disclosed |
| US-20080214620-A1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2008-09-04 | — | — | US | disclosed |
| US-20080153860-A1 | SPIROCYCLIC AZAADAMANTANE DERIVATIVES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2008-06-26 | — | — | US | disclosed |
| WO-2008065141-A1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2008-06-05 | — | — | WO | disclosed |
| US-20070161790-A1 | Process for the preparation of pyrazolo[1,5-a]-1,3,5-triazines and intermediates thereof | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2007-07-12 | — | — | US | disclosed |
| US-7208596-B2 | Processes for the preparation of pyrazolo[1,5-a]-1,3,5-triazines and intermediates thereof | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2007-04-24 | — | — | US | disclosed |
| EP-0009787-B2 | PROCESS FOR THE MONOHALOGENATION OF ALKYLBENZENES IN ALPHA POSITION | BAYER AG (DE) | 1986-07-09 | — | — | EP | disclosed |
| US-4331821-A | ULTRAVIOLET RADIATION OF A VAPORIZED ALKYLBENZEN AND HALOGEN GAS MIXTURE | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-25 | — | — | US | disclosed |
| EP-0009787-B1 | PROCESS FOR THE MONOHALOGENATION OF ALKYLBENZENES IN ALPHA POSITION | BAYER AG (DE) | 1982-01-13 | — | — | EP | disclosed |
| EP-0009787-A2 | Process for the monohalogenation of alkylbenzenes in alpha position | BAYER AG (DE) | 1980-04-16 | — | — | EP | disclosed |