Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1600149 | 0.93 | SCARB1 (1.00) | SCARB1MAPK14 | |
| SCHEMBL1600079 | 0.92 | SCARB1 (0.91) | SCARB1MAPK14 | |
| Itx-5061 Free Base SCHEMBL29437772 | 0.90 | SCARB1 (1.00) | SCARB1MAPK14 | |
| Itx-5061 Free Base SCHEMBL1598868 | 0.90 | SCARB1 (1.00) | SCARB1MAPK14 | |
| SCHEMBL1600446 | 0.89 | SCARB1 (0.83) | SCARB1MAPK14 | |
| SCHEMBL1598950 | 0.89 | SCARB1 (0.86) | SCARB1MAPK14 | |
| SCHEMBL1599677 | 0.89 | SCARB1 (0.96) | SCARB1MAPK14 | |
| Itx-5061 Free Base SCHEMBL29437767 | 0.89 | SCARB1 (0.99) | SCARB1MAPK14 | |
| SCHEMBL1599872 | 0.88 | SCARB1 (0.85) | SCARB1MAPK14 | |
| SCHEMBL1600865 | 0.87 | MAPK14 (0.83) | SCARB1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035005-A2 | THERAPY USING CYTOKINE INHIBITORS | Kemia, INC. (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007146712-A2 | THERAPY USING CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| WO-2006091862-A2 | CYTOKINE INHIBITORS AND THEIR USE IN THERAPY | KEMIA, INC. (US) | 2006-08-31 | — | — | WO | disclosed |