⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7337587 | 0.96 | — | — | |
| SCHEMBL11129097 | 0.69 | — | — | |
| SCHEMBL14422035 | 0.69 | — | — | |
| SCHEMBL5986003 | 0.67 | — | — | |
| SCHEMBL186042 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL3172077 | 0.64 | — | — | |
| SCHEMBL37249 | 0.64 | — | — | |
| SCHEMBL8751500 | 0.62 | TSHR (0.38) | — | |
| SCHEMBL37216 | 0.61 | — | — | |
| SCHEMBL455723 | 0.61 | TP53 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046328-A2 | PYRIDINONE DIKETO ACIDS: INHIBITORS OF HIV REPLICATION IN COMBINATION THERAPY | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2009-04-15 | — | — | EP | claimed |
| WO-2008010953-A2 | PYRIDINONE DIKETO ACIDS: INHIBITORS OF HIV REPLICATION IN COMBINATION THERAPY | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2008-01-24 | — | — | WO | claimed |
| WO-2007106450-A2 | DIKETO ACIDS WITH NUCLEOBASE SCAFFOLDS: ANTI-HIV REPLICATION INHIBITORS TARGETED AT HIV INTEGRASE IN COMBINATION THERAPY | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2007-09-20 | — | — | WO | claimed |
| US-20160318987-A1 | PROTEASE RESISTANT PEPTIDES | MEDIMMUNE LIMITED (GB) | 2016-11-03 | — | — | US | disclosed |
| US-20160237105-A9 | RUTHENIUM CARBON MONOXIDE RELEASING MOLECULES AND USES THEREOF | ALFAMA, INC. (US) | 2016-08-18 | — | — | US | disclosed |
| EP-3050580-A1 | METHOD FOR PRODUCING BIOCOMPATIBLE MACROMOLECULAR POROUS BODY, BIOCOMPATIBLE MACROMOLECULAR POROUS BODY, BIOCOMPATIBLE MACROMOLECULAR BLOCK AND CELL STRUCTURE | FUJIFILM CORPORATION (JP) | 2016-08-03 | — | — | EP | disclosed |
| WO-2016115530-A1 | METHOD AND SYSTEM FOR DETERMINING CANCER STATUS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-07-21 | — | — | WO | disclosed |
| US-20160047040-A1 | NOZZLE FOR UNIFORM PLASMA PROCESSING | APPLIED MATERIALS, INC. | 2016-02-18 | — | — | US | disclosed |
| EP-2985621-A1 | MAGNETIC PROPERTY DETERMINATION DEVICE AND MAGNETIC PROPERTY DETERMINATION METHOD | Glory Ltd. (JP) | 2016-02-17 | — | — | EP | disclosed |
| US-9221762-B2 | Gas and liquid phase catalytic beckmann rearrangement of oximes to produce lactams | HONEYWELL INTERNATIONAL INC. (US) | 2015-12-29 | — | — | US | disclosed |
| US-20150322105-A1 | RUTHENIUM CARBON MONOXIDE RELEASING MOLECULES AND USES THEREOF | ALFAMA, INC. (US) | 2015-11-12 | — | — | US | disclosed |
| EP-2878680-A1 | Genetic polymorphisms associated with cardiovascular diseases, methods of detection and uses thereof | Celera Corporation (US) | 2015-06-03 | — | — | EP | disclosed |
| US-20150126732-A1 | GAS AND LIQUID PHASE CATALYTIC BECKMANN REARRANGEMENT OF OXIMES TO PRODUCE LACTAMS | HONEYWELL INTERNATIONAL INC. (US) | 2015-05-07 | — | — | US | disclosed |
| US-8772476-B2 | Gas and liquid phase catalytic Beckmann rearrangement of oximes to produce lactams | HONEYWELL INTERNATIONAL INC. (US) | 2014-07-08 | — | — | US | disclosed |
| EP-2733222-A1 | Genetic polymorphisms associated with cardiovascular diseases, methods of detection and uses thereof | Celera Corporation (US) | 2014-05-21 | — | — | EP | disclosed |
| US-20130269600-A1 | METHOD FOR GROWING MAGNESIUM-ZINC-OXIDE-BASED CRYSTAL | STANLEY ELECTRIC CO., LTD. (JP) | 2013-10-17 | — | — | US | disclosed |
| US-8500855-B2 | System and method for carbon dioxide capture and sequestration | Global Thermostat Operations, LLC | 2013-08-06 | — | — | US | disclosed |
| US-20130191097-A1 | ERYTHROPOIETIC STIMULATING AGENT (ESA) DOSAGE DETERMINATION | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2013-07-25 | — | — | US | disclosed |
| EP-2607498-A1 | Genetic alterations in isocitrate dehydrogenase and other genes in malignant glioma | The Johns Hopkins University (US) | 2013-06-26 | — | — | EP | disclosed |
| US-8124839-B2 | Identification of terpenoid-biosynthesis related regulatory protein-regulatory region associations | CERES, INC. (US) | 2012-02-28 | — | — | US | disclosed |