Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407866 | 1.00 | TACR1 (0.46) | TACR1CYP3A4SIGMAR1 | |
| SCHEMBL4414388 | 0.90 | TACR1 (0.48) | TACR1CYP3A4SIGMAR1 | |
| SCHEMBL4402090 | 0.90 | TACR1 (0.46) | TACR1CYP3A4SIGMAR1 | |
| SCHEMBL4397488 | 0.90 | TACR1 (0.46) | TACR1CYP3A4SIGMAR1 | |
| SCHEMBL4410342 | 0.89 | TACR1 (0.46) | TACR1 | |
| SCHEMBL4417069 | 0.89 | TACR1 (0.46) | TACR1 | |
| SCHEMBL4398271 | 0.83 | TACR1 (0.54) | TACR1CYP3A4SIGMAR1 | |
| SCHEMBL4406298 | 0.80 | TACR1 (0.46) | TACR1SIGMAR1 | |
| SCHEMBL4408428 | 0.79 | TACR1 (0.45) | TACR1 | |
| SCHEMBL4405783 | 0.79 | TACR1 (0.50) | TACR1CYP3A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005355-A1 | Piperidine Compound and Process for Preparing the Same | TANABE SEIYAKU CO., LTD. (JP) | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005355-A1 | Piperidine Compound and Process for Preparing the Same | AVPR1B, HRH4, PRLHR | TACR1 6/4885CYP3A4 1012/4885SIGMAR1 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.