Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 8/20 | 0.42 |
| ▸ | NPC1 | O15118 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695599 | 0.75 | MAPT (0.45) | RAB9ANPC1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL13379410 | 0.73 | TP53 (0.60) | AMY1AF7HDAC6RAB9ANPC1 | |
| SCHEMBL225143 | 0.72 | IDH1 (0.35) | ALDH1A1SMN1; SMN2TP53LMNAMEN1 | |
| Bisoctrizole SCHEMBL29358089 | 0.70 | NPC1 (0.43) | RAB9ANPC1ALDH1A1SMN1; SMN2HPGD | |
| Bisoctrizole SCHEMBL39191 | 0.70 | NPC1 (0.43) | RAB9ANPC1ALDH1A1SMN1; SMN2HPGD | |
| Bisoctrizole SCHEMBL5994392 | 0.70 | NPC1 (0.43) | RAB9ANPC1ALDH1A1SMN1; SMN2HPGD | |
| Bisoctrizole SCHEMBL30113083 | 0.70 | NPC1 (0.43) | RAB9ANPC1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL17287351 | 0.69 | IDH1 (0.33) | AMY1AALDH1A1SMN1; SMN2TP53MEN1 | |
| Bisoctrizole SCHEMBL26123807 | 0.68 | NPC1 (0.35) | RAB9ANPC1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL4409726 | 0.68 | IDH1 (0.38) | ALDH1A1SMN1; SMN2TP53LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874853-B2 | POLYETHER POLYOLS, POLYESTER POLYOLS AND POLYURETHANES OF LOW RESIDUAL ALDEHYDE CONTENT | BASF SE (DE) | 2012-07-04 | — | — | EP | disclosed |
| EP-1874853-B1 | POLYETHER POLYOLS, POLYESTER POLYOLS AND POLYURETHANES OF LOW RESIDUAL ALDEHYDE CONTENT | CIBA HOLDING INC (CH) | 2009-04-15 | — | — | EP | disclosed |
| EP-0754723-B1 | Synergistic stabiliser mixture | CIBA GEIGY AG (CH) | 1999-04-28 | — | — | EP | disclosed |