SCHEMBL440983

SCHEMBL440983

CCCCCCCCCCCCCCCCCCCCCC(=O)OC(C(=O)CCCCCCCCCCCCCCCCCCCCC)C(O)CO

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.60
MAPK1 P28482 1/20 0.60
LMNA P02545 4/20 0.54
PRKCA P17252 2/20 0.53
PRKCE Q02156 1/20 0.53
PRKCQ Q04759 1/20 0.53
PRKCD Q05655 1/20 0.53
KDM4E B2RXH2 1/20 0.51
DUSP3 P51452 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
ALDH1A1 P00352 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29133986 1.00 MAPT (0.60) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL17003748 1.00 MAPT (0.60) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL611849 1.00 MAPT (0.60) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL1340807 1.00 MAPT (0.60) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL9503022 1.00 MAPT (0.60) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL136431 1.00 MAPT (0.60) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL9055250 1.00 MAPT (0.60) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL1066768 1.00 MAPT (0.60) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL571428 1.00 MAPT (0.60) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL29061395 1.00 MAPT (0.60) MAPTMAPK1LMNAPRKCAPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250099463-A1 Sustained Release Pharmaceutical Composition of Upadacitinib RENATA PHARMACEUTICALS (IRELAND) LIMITED (IE) 2025-03-27 US disclosed
EP-4465971-A1 SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION OF UPADACITINIB Renata Phramaceutical (Ireland) Limited (IE) 2024-11-27 EP disclosed
WO-2023138804-A1 SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION OF UPADACITINIB RENATA PHARMACEUTICAL (IRELAND) LIMITED (IE) 2023-07-27 WO disclosed
EP-3045043-B1 EXTENDED RELEASE ORAL PHARMACEUTICAL COMPOSITIONS OF 3-HYDROXY-N-METHYLMORPHINAN AND METHOD OF USE RELMADA THERAPEUTICS INC (US) 2020-04-29 EP disclosed
EP-3045043-A1 EXTENDED RELEASE ORAL PHARMACEUTICAL COMPOSITIONS OF 3-HYDROXY-N-METHYLMORPHINAN AND METHOD OF USE Relmada Therapeutics, Inc. (US) 2016-07-20 EP disclosed
EP-2448406-B1 EXTENDED RELEASE ORAL PHARMACEUTICAL COMPOSITIONS OF 3-HYDROXY-N-METHYLMORPHINAN AND METHOD OF USE RELMADA THERAPEUTICS INC (US) 2016-04-20 EP disclosed
WO-2013030726-A1 PROGRAMMED DRUG DELIVERY WOCKHARDT LIMITED (IN) 2013-03-07 WO disclosed
EP-2448406-A1 EXTENDED RELEASE ORAL PHARMACEUTICAL COMPOSITIONS OF 3-HYDROXY-N-METHYLMORPHINAN AND METHOD OF USE Relmada Therapeutics, Inc. (US) 2012-05-09 EP disclosed
US-20120065221-A1 Extended Release Oral Pharmaceutical Compositions of 3-Hydroxy-N-Methylmorphinan and Method of Use THERAQUEST BIOSCIENCES, INC. (PA) 2012-03-15 US disclosed
WO-2010099508-A1 EXTENDED RELEASE ORAL PHARMACEUTICAL COMPOSITIONS OF 3-HYDROXY-N-METHYLMORPHINAN AND METHOD OF USE THERAQUEST BIOSCIENCES, INC. (US) 2010-09-02 WO disclosed
US-20080038342-A1 Stable Pharmaceutical Composition Comprising an Ace Inhibitor NICHE GENERICS LIMITED (GB) 2008-02-14 US disclosed
EP-1729812-A1 STABLE PHARMACEUTICAL COMPOSITION COMPRISING AN ACE INHIBITOR Niche Generics Limited (GB) 2006-12-13 EP disclosed
WO-2005082420-A1 STABLE PHARMACEUTICAL COMPOSITION COMPRISING AN ACE INHIBITOR NICHE GENERICS LIMITED (GB) 2005-09-09 WO disclosed
EP-0319126-B1 Process for preparation of polyol fatty acid ester and glyceride mixture obtained KAO CORP (JP) 1995-11-08 EP disclosed
US-5461170-A Diglyceride from branched and straight chain fatty acids KAO CORPORATION (JP) 1995-10-24 US disclosed
EP-0658629-A1 Process for preparation of polyol fatty acid ester and glyceride mixture obtained Kao Corporation (JP) 1995-06-21 EP disclosed
EP-0319126-A2 Process for preparation of polyol fatty acid ester and glyceride mixture obtained Kao Corporation (JP) 1989-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080038342-A1 Stable Pharmaceutical Composition Comprising an Ace Inhibitor ACE, ACE2, AGT MAPT 2144/4885MAPK1 2908/4885LMNA 1458/4885
US-20250099463-A1 Sustained Release Pharmaceutical Composition of Upadacitinib PLAUR, JAK1, P2RY13 MAPT 2785/4885MAPK1 2227/4885LMNA 3449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.