Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 2/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 13/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 7/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2935037 | 0.83 | MAPK14 (0.47) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL2931590 | 0.82 | MAPK14 (0.49) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL4408452 | 0.82 | MAPK14 (0.49) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL4408117 | 0.80 | MAPK14 (0.47) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL1385351 | 0.78 | CDK2 (0.51) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL6579207 | 0.78 | MAPK14 (0.53) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL2926468 | 0.77 | MAPK14 (0.48) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL1386407 | 0.76 | MAPK14 (0.52) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL2926388 | 0.75 | MAPK14 (0.53) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL4407549 | 0.75 | MAPK14 (0.48) | CSNK1ECCNA2CDK2CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264446-A9 | Condensed Pyridines as Kinase Inhibitors | PALAU PHARMA, S.A. (ES) | 2009-10-22 | — | — | US | disclosed |
| US-20080318977-A1 | Condensed Pyridines as Kinase Inhibitors | PALAU PHARMA, S.A. (ES) | 2008-12-25 | — | — | US | disclosed |
| EP-1833828-A2 | CONDENSED PYRIDINES AS KINASE INHIBITORS | Palau Pharma, S.A. (ES) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006013095-A2 | CONDENSED PYRIDINES AS KINASE INHIBITORS | PALAU PHARMA, S.A. (ES) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264446-A9 | Condensed Pyridines as Kinase Inhibitors | MAPK1, MAP4K2, MAP3K1 | CSNK1E 134/4885CCNA2 443/4885CDK2 33/4885 |
| US-20080318977-A1 | Condensed Pyridines as Kinase Inhibitors | MAPK1, MAP4K2, MAP3K1 | CSNK1E 134/4885CCNA2 443/4885CDK2 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.