Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 4/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.41 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | CD99 | P14209 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3407883 | 1.00 | SLC5A2 (0.41) | SLC5A2SLC5A1SLC28A2ADORA3ADORA2A | |
| SCHEMBL3407881 | 1.00 | SLC5A2 (0.41) | SLC5A2SLC5A1SLC28A2ADORA3ADORA2A | |
| SCHEMBL4411202 | 1.00 | SLC5A2 (0.41) | SLC5A2SLC5A1SLC28A2ADORA3ADORA2A | |
| SCHEMBL3407262 | 0.92 | CYP11B1 (0.41) | SLC5A2SLC5A1SLC28A2CYP11B1CYP11B2 | |
| SCHEMBL3407267 | 0.92 | CYP11B1 (0.41) | SLC5A2SLC5A1SLC28A2CYP11B1CYP11B2 | |
| SCHEMBL4416146 | 0.92 | CYP11B1 (0.41) | SLC5A2SLC5A1SLC28A2CYP11B1CYP11B2 | |
| SCHEMBL4416143 | 0.92 | CYP11B1 (0.41) | SLC5A2SLC5A1SLC28A2CYP11B1CYP11B2 | |
| SCHEMBL3410079 | 0.86 | SLC5A2 (0.41) | SLC5A2SLC5A1 | |
| SCHEMBL3407894 | 0.86 | SLC5A2 (0.41) | SLC5A2SLC5A1 | |
| SCHEMBL3407900 | 0.86 | SLC5A2 (0.41) | SLC5A2SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1679966-A4 | SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES | JANSSEN PHARMACEUTICA NV (BE) | 2009-05-27 | — | — | EP | claimed |
| EP-1679966-A2 | SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-07-19 | — | — | EP | claimed |
| WO-2005012242-A2 | SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES | JANSSEN PHARMACEUTICA NV (BE) | 2005-02-10 | — | — | WO | claimed |