SCHEMBL441192

SCHEMBL441192

C=C(C)C(=O)OCCO.N#CC=CC=Cc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.38
LMNA P02545 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TDP1 Q9NUW8 4/20 0.37
CYP3A4 P08684 1/20 0.37
KDM4E B2RXH2 2/20 0.37
MCL1 Q07820 2/20 0.36
AKR1B10 O60218 1/20 0.36
AKR1B1 P15121 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
ALDH1A1 P00352 6/20 0.35
MAPT P10636 2/20 0.35
RECQL P46063 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
GLA P06280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27571337 0.96 POLB (0.36) POLBLMNASMN1; SMN2NPC1RAB9A
SCHEMBL7041907 0.94 CYP3A4 (0.36) POLBLMNASMN1; SMN2NPC1RAB9A
SCHEMBL3257562 0.89 POLB (0.40) POLBLMNASMN1; SMN2NPC1RAB9A
Hydrochloric Acid SCHEMBL28414779 0.88 POLB (0.37) POLBLMNASMN1; SMN2NPC1RAB9A
SCHEMBL5028546 0.88 TDP1 (0.51) POLBLMNASMN1; SMN2NPC1RAB9A
Hydrochloric Acid SCHEMBL28415582 0.87 CHRM1 (0.40) POLBLMNASMN1; SMN2NPC1RAB9A
SCHEMBL11872611 0.86 MAPT (0.44) LMNASMN1; SMN2NPC1RAB9AL3MBTL1
SCHEMBL10585936 0.85 BCHE (0.43) POLBLMNASMN1; SMN2RAB9ACYP3A4
SCHEMBL9724589 0.85 TDP1 (0.50) POLBLMNASMN1; SMN2NPC1RAB9A
SCHEMBL28003480 0.85 TDP1 (0.50) POLBLMNASMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0558262-B1 Low gloss polycarbonate/ABS blends GEN ELECTRIC (US) 1998-08-05 EP claimed
US-5310791-A Reduced surface gloss; molding resins GENERAL ELECTRIC COMPANY (US) 1994-05-10 US claimed
EP-0558262-A1 Low gloss polycarbonate/ABS blends GENERAL ELECTRIC COMPANY (US) 1993-09-01 EP claimed
WO-2024116569-A1 RATTLE NOISE REDUCTION MATERIAL AND THERMOPLASTIC RESIN COMPOSITION テクノUMG株式会社 2024-06-06 WO disclosed
CN-117940498-A Thermoplastic resin composition for foam molding and foam molded article thereof 大科能宇菱通株式会社 2024-04-26 CN disclosed
EP-4310144-A1 THERMOPLASTIC COMPOSITION AND MOLDED PRODUCT THEREOF Techno-UMG Co., Ltd. (JP) 2024-01-24 EP disclosed
EP-4296312-A1 THERMOPLASTIC RESIN COMPOSITION FOR FOAM MOLDING, AND FOAM MOLDED ARTICLE THEREOF Techno-UMG Co., Ltd. (JP) 2023-12-27 EP disclosed
US-20230383079-A1 THERMOPLASTIC RESIN COMPOSITION FOR FOAM MOLDING AND MOLDED FOAM ARTICLE THEREOF TECHNO-UMG CO., LTD. (JP) 2023-11-30 US disclosed
CN-116685640-A Thermoplastic composition and molded article thereof 大科能宇菱通株式会社 2023-09-01 CN disclosed
US-11739209-B2 Thermoplastic composition and molded article thereof TECHNO-UMG CO., LTD. (JP) 2023-08-29 US disclosed
CN-116368190-A Thermoplastic resin composition for foam molding and foam molded article thereof 大科能宇菱通株式会社 2023-06-30 CN disclosed
EP-2070985-A1 THERMOPLASTIC RESIN COMPOSITION AND RESIN MOLDED ARTICLE Techno Polymer Co., Ltd. (JP) 2009-06-17 EP disclosed
EP-2048200-A1 THERMOPLASTIC POLYMER COMPOSITION AND MOLDED ARTICLE Techno Polymer Co., Ltd. (JP) 2009-04-15 EP disclosed
US-20070208114-A1 Flame Retardant Resin Composition and Molded Article TECHNO POLYMER CO., LTD. (JP) 2007-09-06 US disclosed
CN-1946805-A Thermoplastic resin composition and resin molded product TECHNO POLYMER CO LTD (JP) 2007-04-11 CN disclosed
US-5430101-A Containing copolymer having epoxy group but no olefin and copolymer of aromatic vinyl and functional, ethylenically unsaturated compounds; auto interiors, business machine parts SUMITOMO DOW LIMITED (JP) 1995-07-04 US disclosed
US-5302646-A Flame retardancy; molding resins GENERAL ELECTRIC COMPANY (US) 1994-04-12 US disclosed
EP-0312001-B1 Thermoplastic resin composition SUMITOMO DOW LTD (JP) 1994-01-05 EP disclosed
EP-0558266-A1 Low gloss flame-retarded polycarbonate/ABS blends GENERAL ELECTRIC COMPANY (US) 1993-09-01 EP disclosed
EP-0312001-A2 Thermoplastic resin composition Sumitomo Dow Limited (JP) 1989-04-19 EP disclosed