Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA3 | P07451 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837333 | 0.83 | LCK (0.67) | NPC1RAB9ACASP3SENP7SENP6 | |
| SCHEMBL4412268 | 0.79 | NPC1 (0.60) | NPC1RAB9ACASP3SENP7SENP6 | |
| SCHEMBL216822 | 0.76 | NPC1 (1.00) | NPC1RAB9ACASP3SENP7SENP6 | |
| SCHEMBL10812793 | 0.76 | KMT2A (0.66) | NPC1RAB9ACASP3SENP7SENP6 | |
| SCHEMBL31474878 | 0.76 | KMT2A (0.66) | NPC1RAB9ACASP3SENP7SENP6 | |
| SCHEMBL8837282 | 0.73 | NPC1 (0.82) | NPC1RAB9ACASP3SENP7SENP6 | |
| SCHEMBL279860 | 0.69 | MAOB (0.77) | NPC1RAB9AKDM4EALDH1A1CA12 | |
| SCHEMBL29539474 | 0.69 | MAOB (0.77) | NPC1RAB9AKDM4EALDH1A1CA12 | |
| SCHEMBL34468463 | 0.69 | MAOB (0.77) | NPC1RAB9AKDM4EALDH1A1CA12 | |
| Coumarin-3-Carboxylic Acid SCHEMBL93571 | 0.68 | MAOB (1.00) | NPC1RAB9AKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635491-B2 | Method for administering selenium for treating patients suffering from systemic inflammatory response syndrome (SIRS), and composition for implementing the treatment | Forceville, Xavier (FR) | 2009-12-22 | — | — | US | disclosed |